Evidence map›Paper›PMID 25154713›Full record

ArticleScientific reports2014

Processing and characterisation of a novel electropolymerized silk fibroin hydrogel membrane.

Hai-Yan Wang, Yu-Qing Zhang

Abstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Chitosan hydrogel/silk fibroin/Mg(OH)Scientific reports · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Silk scaffolds for musculoskeletal tissue engineering.Experimental biology and medicine (Maywood, N.J.) · 2016
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hai-Yan WangSilk Biotechnology Laboratory, School of Biology and Basic Medical Sciences, Soochow University; RM702-2303, No. 199, Renai Road, Dushuhu Higher Edu. Town, Suzhou 215123; P. R. China.
Yu-Qing ZhangSilk Biotechnology Laboratory, School of Biology and Basic Medical Sciences, Soochow University; RM702-2303, No. 199, Renai Road, Dushuhu Higher Edu. Town, Suzhou 215123; P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silk fibroin can be made into various forms of biocompatible medical materials, including hydrogel due to its excellent properties. Here, we report a novel method for the preparation of electropolymerized silk fibroin hydrogel membrane (ESFHM), which is formed on a nanoporous film as a barrier using a homemade device at a higher DC voltage. Regenerated silk fibroin solution in Tris buffer (pH 6.55-7.55) was added into a reservoir with a negative charge, and the silk molecules migrated toward the positive charge at 80VDC, resulting in the formation of the ESFHM on the barrier film. Barrier film with a MWCO of 10 kDa is favourable to the formation of the ESFHM. Semi-transparent ESFHM with a swelling ratio of 1056.4% predominantly consisted of a mixture of β-sheets and α-helix crystalline structures. SEM studies revealed that the ESFHM consisted of a 3D mesh structure woven by a chain of silk fibroin nanoparticles with a size of approximately 30 nanometres, similar to a pearl necklace. In vitro studies indicated that the ESFHM was degradable and was sufficient for cell adhesion and growth. Thus, ESFHM is a promising candidate for loading bioactive protein and appropriate cells, as artificial skin or for use in transplantation.

Indexed as

AnimalsBiocompatible MaterialsCell AdhesionCell LineCompressive StrengthElectrochemical TechniquesFibroinsHydrogelsHydrogen-Ion ConcentrationMaterials TestingMiceNanostructuresPolymerizationPorositySodium Dodecyl SulfateSpectroscopy, Fourier Transform InfraredBiocompatible MaterialsFibroinsHydrogelsSodium Dodecyl SulfateSurface-Active Agents

Identifiers

PMID25154713
PMCPMC4143793

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.