Evidence map›Paper›PMID 25154674›Full record

ArticleFertility and sterility2014

Prospective study of depression and anxiety in female fertility preservation and infertility patients.

Angela K Lawson, Susan C Klock, Mary Ellen Pavone, Jennifer Hirshfeld-Cytron, Kristin N Smith, Ralph R Kazer

Registry-linked trialAbstract readControlled Clinical Trial
In one paragraph

Article in Fertility and sterility, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03031990 (Yoga and Infertility), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03031990 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Yoga and Infertility: The Impact of Yoga on Anxiety Reduction in Patients Undergoing in Vitro Fertilization or Elective Oocyte Freezing

TypeinterventionalSponsorFertility Centers of IllinoisRan2017 to 2017Enrolled300ConditionsAnxiety, Infertility, FemaleArmsIn-person yoga for fertility group, Online yoga for fertility group, In person discussion only group
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

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  18. Early β-hCG levels predict live birth after single embryo transfer.Journal of assisted reproduction and genetics · 2022
    Article
  19. Psychological State and Decision Perceptions of Male and Female Cancer Patients on Fertility Preservation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Angela K LawsonNorthwestern University, Chicago, Illinois. Electronic address: alawson@nmff.org.
Susan C KlockNorthwestern University, Chicago, Illinois.
Mary Ellen PavoneNorthwestern University, Chicago, Illinois.
Jennifer Hirshfeld-CytronFertility Centers of Illinois, Orland Park, Illinois.
Kristin N SmithNorthwestern University, Chicago, Illinois.
Ralph R KazerNorthwestern University, Chicago, Illinois.
Northwestern University · USFertility Centers of Illinois · US

Funding

Research Career Development in Obstetrics and GynecologyK12HD050121 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Serdar E. Bulun · 2005 to 2026
$7.2M
Project 3: Medically-based Protection of the Ovarian Reserve Against Anti-CancerP50HD076188 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHANG, R JEFFREY · 2014 to 2017
$6.2M
U54: The Oncofertility Consortium: Fertility Preservation for Woman (1 of 10)UL1DE019587 · NIDCR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOODRUFF, TERESA K · 2008 to 2011
$3.7M
Project 3: Medically-based Protection of the Ovarian Reserve Against Anti-CancerU54HD076188 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOODRUFF, TERESA K · 2013 to 2013
$1.6M
NICHD NIH HHS K12 HD050121NICHD NIH HHS K12HD050121NICHD NIH HHS P50 HD076188NICHD NIH HHS U54 HD076188NICHD NIH HHS U54HD076188NIDCR NIH HHS UL1 DE019587NIDCR NIH HHS UL1DE019587
6 · The paper itself

Abstract

objectiveTo prospectively assess anxiety, depression, coping, and appraisal in female fertility preservation (FP) patients compared with infertile patients.

designProspective pre- and post-treatment survey.

settingAcademic medical center. PATIENT(S): Forty-seven women with cancer (FP patients) and 91 age-matched infertile patients. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Depression, anxiety, coping, infertility-related stress, appraisal of treatment, and medical outcomes. RESULT(S): FP patients reported more symptoms of anxiety and depression than infertile patients, but infertile patients' symptoms worsened over time; 44% of FP and 14% of infertile patients' scores exceeded the clinical cutoff for depression before treatment. The interval between surveys and medical treatment data did not predict changes in mood symptoms. Coping strategies and infertility-related stress did not differ between groups, and avoidant coping predicted higher depression and anxiety scores. CONCLUSION(S): FP patients reported more anxiety and depression than infertile patients at enrollment in treatment, with more than one-third of FP patients reporting clinically significant depressive symptoms. However, infertile patients' anxiety and depressive symptoms increased across treatment. This increase was not related to time between registration for IVF and oocyte retrieval or the medical aspects of treatment. FP and infertile patients should be provided psychologic consultation before treatment to identify mood and anxiety symptoms and to refer patients for counseling as needed to prevent worsening of symptoms.

Indexed as

Adaptation, PsychologicalAdultAnxietyCausalityComorbidityDepressionFemaleFertility PreservationFertilization in VitroHumansIllinoisIncidenceInfertility, FemalePregnancyRisk FactorsTreatment OutcomecounselingFertility preservationIVFpsychologic

Identifiers

PMID25154674
PMCPMC4253550
OpenAlexW1979276720

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.