Evidence map›Paper›PMID 25152841›Full record

ArticleInnovations in clinical neuroscience2014

Anosognosia in schizophrenia: hidden in plain sight.

Douglas S Lehrer, Jennifer Lorenz

Open access · greenAbstract read
In one paragraph

Article in Innovations in clinical neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
32.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Frontal Disorders and Consciousness: A Review.Current neurology and neuroscience reports · 2025
    Review
  5. Review
  6. Review
  7. Anosognosia in schizophrenia.CNS spectrums · 2024
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Insight and Psychosis.Indian journal of psychological medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Douglas S LehrerDr. Lehrer is from Wright State University Boonshoft School of Medicine, Department of Psychiatry, Dayton, Ohio, and Summit Behavioral Healthcare, Cincinnati, Ohio; Dr. Lorenz is from Wright State University Boonshoft School of Medicine, Department of Psychiatry, Dayton, Ohio, and USAF Medical Center, Wright-Patterson Air Force Base, Department of Mental Health, Ohio.
Jennifer LorenzDr. Lehrer is from Wright State University Boonshoft School of Medicine, Department of Psychiatry, Dayton, Ohio, and Summit Behavioral Healthcare, Cincinnati, Ohio; Dr. Lorenz is from Wright State University Boonshoft School of Medicine, Department of Psychiatry, Dayton, Ohio, and USAF Medical Center, Wright-Patterson Air Force Base, Department of Mental Health, Ohio.
Wright State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePoor insight is a cardinal symptom of schizophrenia that, while not universally and uniformly expressed in all patients, is among the most common of its manifestations. Available neurobiological and neurocognitive evidence linking the phenomenon to core pathophysiology of schizophrenia justifies extension of the anosognosia construct to schizophrenia-related insight deficits. Poor insight is a core attribute of schizophrenia, occurring in 57 to 98 percent of patients. Insight is an important outcome predictor, associated with treatment adherence, relapse frequency, symptom remission, psychosocial functioning, vocational attainment, and risk of violence toward self or others. Combined findings lend urgency to the importance of reducing psychotic relapse. This can only be achieved in the majority of patients with consistent medication adherence- something that is often exceedingly difficult in patients lacking belief in the fact of their illness. This article examines whether anosognosia, the unawareness of deficit or illness, should apply to our understanding of insight deficits in patients with schizophrenia. Although research in the field is limited at this time, there is hope that anosognosia as a symptom of schizophrenia will become a focus of further research and a critically important therapeutic target amenable to treatment.

designThis article is a literature review and conceptualization.

conclusionLimited research in the field gives cause for hope that anosognosia as a symptom of schizophrenia will become a critically important therapeutic target that is amendable to treatment.

Indexed as

anosognosiacognitioninsightpsychosisSchizophrenia

Identifiers

PMID25152841
PMCPMC4140620
OpenAlexW1862162680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.