Evidence map›Paper›PMID 25152804›Full record

ReviewThe World Allergy Organization journal2014

Asthma in the elderly: what we know and what we have yet to know.

Anahí Yáñez, Sang-Hoen Cho, Joan B Soriano, Lanny J Rosenwasser, Gustavo J Rodrigo, Klaus F Rabe, Stephen Peters, Akio Niimi, Dennis K Ledford, Rohit Katial and 10 more

Open access · goldAbstract readReview
In one paragraph

Review in The World Allergy Organization journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Aging, brain-derived neurotrophic factor, and allergen-induced pulmonary responses in mice.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Life Course of Asthma.Advances in experimental medicine and biology · 2023
    Article
  15. Management of Elderly Asthma: Key Questions and Tentative Answers.Allergy, asthma & immunology research · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Socioeconomic-related determinants of asthma in the elderly.Journal of preventive medicine and hygiene · 2020
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 18 institutions in 10 countries.

Anahí YáñezInvestigaciones en Alergia y Enfermedades Respiratorias- InAER, Buenos Aires, Argentina.
Sang-Hoen ChoDepartment of Internal Medicine, Hanyang University Hospital, Seoul, South Korea.
Joan B SorianoPrograma de Epidemiologia e Investigacion Clinica, Fundación Caubet-CIMERA, Illes Balears, Spain.
Lanny J RosenwasserChildren's Mercy Hospital, University of Missouri - Kansas City School of Medicine, Kansas City, Missoui, United States of America.
Gustavo J RodrigoDepartamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay.
Klaus F RabeKrankenhaus Lungen Clinic, Grosshansdorf, Germany.
Stephen PetersWake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Akio NiimiDepartment of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, Kyoto, Japan.
Dennis K LedfordDivision of Allergy and Immunology, Department of Medicine, Morsani University of South Florida College of Medicine, James A Haley Veterans Hospital, Tampa, Florida, United States of America.
Rohit KatialDivision of Allergy and Immunology, National Jewish Health, Denver, Colorado, United States of America.
Leonardo M FabbriDepartment of Oncology, Haematology, and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Juan C CeledónDivision of Pulmonary Medicine, Allergy and Immunology, Children's Hospital of UPMC, Pittsburgh, Pennsylvania, United States of America.
Giorgio Walter CanonicaRespiratory Diseases and Allergy, University of Genoa, Genoa, Italy.
Paula BusseDivision of Clinical Immunology, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America.
Louis-Phillippe BouletInstitut universitaire de cardiologie et de pneumologie de Québec, (Quebec Heart and Lung Institute, Laval University), Quebéc, Canada.
Carlos E Baena-CagnaniCentre for Research in Respiratory Medicine, Catholic University of Córdoba, Córdoba, Argentina.
Qutayba HamidMeakins-Christie Laboratories, McGill University, Quebéc, Canada.
Claus BachertUpper Airways Research Laboratory (URL), Clinics ENT-Department, University Hospital Ghent, Ghent, Belgium.
Ruby PawankarDepartment of Pediatrics, Nippon Medical School, Tokyo, Japan.
Stephen T HolgateFaculty of Medicine Clinical and Experimental Sciences, University of Southampton, Hampshire, United Kingdom.
Administración Nacional de Laboratorios e Institutos de Salud · ARGhent University Hospital · BEHanyang University Seoul Hospital · KRHospital Central de las Fuerzas Armadas · UYIcahn School of Medicine at Mount Sinai · USInstitut universitaire de cardiologie et de pneumologie de Québec · CAJames A. Haley Veterans' Hospital · USLungenClinic Grosshansdorf · DEMcGill University · CANagoya City University · JPNippon Medical School · JPUniversidad Católica de Córdoba · ARUniversity of Colorado Denver · USUniversity of Genoa · ITUniversity of Missouri–Kansas City · USUniversity of Modena and Reggio Emilia · ITUniversity of Southampton · GBWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past, asthma was considered mainly as a childhood disease. However, asthma is an important cause of morbidity and mortality in the elderly nowadays. In addition, the burden of asthma is more significant in the elderly than in their younger counterparts, particularly with regard to mortality, hospitalization, medical costs or health-related quality of life. Nevertheless, asthma in the elderly is still been underdiagnosed and undertreated. Therefore, it is an imperative task to recognize our current challenges and to set future directions. This project aims to review the current literature and identify unmet needs in the fields of research and practice for asthma in the elderly. This will enable us to find new research directions, propose new therapeutic strategies, and ultimately improve outcomes for elderly people with asthma. There are data to suggest that asthma in older adults is phenotypically different from young patients, with potential impact on the diagnosis, assessment and management in this population. The diagnosis of AIE in older populations relies on the same clinical findings and diagnostic tests used in younger populations, but the interpretation of the clinical data is more difficult. The challenge today is to encourage new research in AIE but to use the existing knowledge we have to make the diagnosis of AIE, educate the patient, develop a therapeutic approach to control the disease, and ultimately provide a better quality of life to our elderly patients.

Identifiers

PMID25152804
PMCPMC4137434
OpenAlexW2097044670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.