ArticleThe open cardiovascular medicine journal2014
Acute coronary syndrome in the young: clinical characteristics, risk factors and prognosis.
Article in The open cardiovascular medicine journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 65 citations in OpenAlex.
- Effect of factor XIII levels and polymorphisms on the risk of myocardial infarction in young patients.Molecular and cellular biochemistry · 2018Trial
- Clinical and Angiographic Profile of Acute Coronary Syndrome in Adults Under 40 Years: A Cross-sectional Observational Study.Annals of African medicine · 2026Observational
- Circulating exosomal miRNA in acute coronary syndrome: mechanisms, clinical relevance and future directions.Frontiers in molecular biosciences · 2026Review
- Cholesterol-to-Lymphocyte Ratio as a Predictor of 1-Year Unplanned Readmission in Patients with Coronary Artery Disease and Type 2 Diabetes Mellitus: A Retrospective Cohort Study.International journal of general medicine · 2026Article
- Atypical Presentation of Behçet Disease Unmasked by Acute Coronary Syndrome.JACC. Case reports · 2025Article
- Coronary Artery Disease in Very Young Women: Risk Factors and Prognostic Insights from Extended Follow-Up.Journal of cardiovascular development and disease · 2025Article
- OCT-based comparative evaluation of culprit lesion morphology in very young versus older adult patients with STEMI.AsiaIntervention · 2024Article
- Acute coronary syndrome in young (≤45 years) patients: a multi-centre observational study.Annals of medicine and surgery (2012) · 2024Article
- Characteristics and treatment analysis of young acute coronary syndrome patients in a tertiary care hospital: A cross-sectional retrospective study.Health science reports · 2023Article
- Presentation, Management and Early Mortality of Patients with Acute Coronary Syndrome in a Large Sample Study of a Middle East Country.International journal of preventive medicine · 2023Article
- Article
- Inferior STEMI Electrocardiogram in a Young Postpartum Female with Sickle Cell Trait with Chest Pain - A Case Report.Journal of education & teaching in emergency medicine · 2022Article
- Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up.Journal of cardiovascular development and disease · 2022Article
- The Prevalence of Erectile Dysfunction and Its Association with Cardiovascular Risk Factors in Patients after Myocardial Infarction.Medicina (Kaunas, Lithuania) · 2021Article
- Long-Term Prognosis in Young Patients with Acute Coronary Syndrome Treated with Percutaneous Coronary Intervention.Vascular health and risk management · 2021Article
- Comparative assessment of clinical profile and outcomes after primary percutaneous coronary intervention in young patients with singleWorld journal of cardiology · 2020Article
- Comparison of Patients with Acute Myocardial Infarction According to Age.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2019Article
- Analysis of the Blood Viscosity Behavior in the Sicilian Study on Juvenile Myocardial Infarction.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018Article
- Hypertension Is an Independent Predictor of Multivessel Coronary Artery Disease in Young Adults with Acute Coronary Syndrome.International journal of hypertension · 2018Article
- Two-year prognosis after acute coronary syndrome in younger patients: Association with feeling depressed in the prior year, and BDI-II score and Endothelin-1.Journal of psychosomatic research · 2017Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo describe the characteristics of patients ≤40 years of age hospitalized for acute coronary syndrome, analyze the risk factors and identify the variables associated with prognosis.
methodsCase series of patients admitted between 2003 and 2012 inclusive in a tertiary hospital (123 consecutive cases admitted between 2003 and 2012), and case-control study (369 controls selected from the general population matched for sex and age with cases, at a ratio of 3:1). OUTCOME VARIABLES: Mortality, likelihood of survival without readmission for heart-related problems, extent of coronary disease as determined by coronary angiography and cardiovascular risk factors.
resultsMean age was 35.4±4.8 years and 83.7% of the participants were men. Myocardial infarction with abnormal Q wave (48%) and single-vessel involvement (44.7%) predominated. Intrahospital mortality was 1.6%. For the 108 patients eventually included in the follow-up, likelihood of readmission-free survival after 60 months was 69.3±4.8%. In the case group 36% of the patients admitted to using cocaine. Compared to controls, the prevalence in patients was higher for smoking (74.8 vs 33.1%, p<0001), diabetes (14.6% vs 5.1%, p=0.001), low HDL-cholesterol (82.9 vs 34.1%, p<0.001) and obesity (30.0 vs 20.3%, p=0.029). Decreased left ventricular ejection fraction (odds ratio=2.2, p=0.033) and smoking (odds ratio=7.8, p=0.045) were associated with readmission for coronary syndrome.
conclusionAcute coronary syndrome in people younger than 40 years is associated with diabetes and unhealthy lifestyle: smoking, sedentary behavior (low HDL-cholesterol), cocaine use and obesity. The readmission rate is high, and readmission is associated with smoking and decreased ejection fraction.
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