ArticleDialogues in clinical neuroscience2014
The assessment of quality of life in clinical practice in patients with schizophrenia.
Article in Dialogues in clinical neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Progressive Muscle Relaxation Therapy in Patients With Schizophrenia: Randomized Controlled Trials
Social Cognition Individualized Activities Lab (SoCIAL) for the Training of Social Cognition and Narrative Enhancement in Patients With Schizophrenia: A Randomized Controlled Study to Assess Efficacy and Generalization to Real-life Functioning
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Schizophrenia Quality of Life Scale and Schizophrenia Quality of Life Scale Revision 4: A Systematic Review of Measurement Properties.Schizophrenia bulletin · 2025Pooled it
- Exercise to treat psychopathology and other clinical outcomes in schizophrenia: A systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2023Pooled it
- Quality of life in schizophrenia: Symptomatic markers of improvement over time.Psychiatric rehabilitation journal · 2026Trial
- Quality of life in early-phase schizophrenia patients starting treatment with long-acting injectable vs. oral antipsychotic drugs: Data from the European Long-acting Antipsychotics in Schizophrenia Trial (EULAST).European psychiatry : the journal of the Association of European Psychiatrists · 2026Trial
- Multidimensional Assessment of Functional Outcomes in Schizophrenia: Results From QUALIFY, a Head-to-Head Trial of Aripiprazole Once-Monthly and Paliperidone Palmitate.The international journal of neuropsychopharmacology · 2017Trial
- Quality of life assessment in individuals with schizophrenia: a COSMIN-based systematic review of S-QoL41 and S-QoL18 incorporating neurobiological support.EClinicalMedicine · 2026Review
- Schizophrenia Impacts and Treatment Priorities: Results of An Externally-Led Patient-Focused Drug Development Meeting Survey.Therapeutic innovation & regulatory science · 2026Article
- Moroccan Arabic adaptation and cross cultural validation of the Schizophrenia Quality of Life short version questionnaire SQoL 18 in individuals with schizophrenia.Discover mental health · 2026Article
- Unraveling the complex relationships between anxiety, depression, and quality of life in schizophrenia: a network analysis study.European archives of psychiatry and clinical neuroscience · 2026Article
- Schizophrenia.Nature reviews. Disease primers · 2025Review
- Association of psychosis and oral health: case-control study.Clinical oral investigations · 2025Article
- Impact of mental disorders on health-related quality of life: a propensity score matched comparison.Frontiers in psychiatry · 2025Article
- Symptom contributors to quality of life in schizophrenia: Exploratory factor and network analyses.Schizophrenia research · 2024Article
- Systematic Literature Review of Studies Reporting Measures of Functional Outcome or Quality of Life in People with Negative Symptoms of Schizophrenia.Patient related outcome measures · 2024Review
- A review on the pharmacology of cariprazine and its role in the treatment of negative symptoms of schizophrenia.Frontiers in psychiatry · 2024Review
- Investigation of Neurocognitive Deficits, Quality of Life, and Functional Performance in Ultra-High-Risk Individuals Compared to Familial High-Risk Individuals for Schizophrenia.Iranian journal of psychiatry · 2023Article
- A Community Navigation Scale for Persons With Serious Mental Illnesses.Psychiatric services (Washington, D.C.) · 2022Article
- Factors associated with health-related quality of life in long-stay inpatients with chronic schizophrenia.PCN reports : psychiatry and clinical neurosciences · 2022Article
- Assessment of Quality of Life 8-Dimension (AQoL-8D): translation, validation, and application in two Dutch trials in patients with epilepsy and schizophrenia.Expert review of pharmacoeconomics & outcomes research · 2022Article
- Impact of Negative Symptoms on Functioning and Quality of Life in First Psychotic Episodes of Schizophrenia.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present article is to review QoL scales used in studies investigating patients with schizophrenia over the past 5 years, and to summarize the results of QoL assessment in clinical practice in these patients. Literature available from January 2009 to December 2013 was identified in a PubMed search using the key words "quality of life" and "schizophrenia" and in a cross-reference search for articles that were particularly relevant. A total of n=432 studies used 35 different standardized generic and specific QoL scales in patients with schizophrenia. Affective symptoms were major obstacles for QoL improvement in patients with schizophrenia. Though positive symptoms, negative symptoms, and cognitive functioning may be seen as largely independent parameters from subjective QoL, especially in cross-sectional trials, long-term studies confirmed a critical impact of early QoL improvement on long-term symptomatic and functional remission, as well as of early symptomatic response on long-term QoL. Results of the present review suggest that QoL is a valid and useful outcome criterion in patients with schizophrenia. As such, it should be consistently applied in clinical trials. Understanding the relationship between symptoms and functioning with QoL is important because interventions that focus on symptoms of psychosis or functioning alone may fail to improve subjective QoL to the same level. However, the lack of consensus on QoL scales hampers research on its predictive validity. Future research needs to find a consensus on the concept and measures of QoL and to test whether QoL predicts better outcomes with respect to remission and recovery under consideration of different treatment approaches in patients with schizophrenia.
Indexed as
Identifiers
25152657PMC4140512What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.