Evidence map›Paper›PMID 25152300›Full record

ArticleThe journal of pain2014

Guideline-concordant management of opioid therapy among human immunodeficiency virus (HIV)-infected and uninfected veterans.

Julie R Gaither, Joseph L Goulet, William C Becker, Stephen Crystal, E Jennifer Edelman, Kirsha Gordon, Robert D Kerns, David Rimland, Melissa Skanderson, Daniel F Weisberg and 2 more

Abstract read
In one paragraph

Article in The journal of pain, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Improving the Delivery of Chronic Opioid Therapy Among People Living With Human Immunodeficiency Virus: A Cluster Randomized Clinical Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Brief Report: Longitudinal Opioid Use Among HIV-Infected Patients, 2000 to 2014.Journal of acquired immune deficiency syndromes (1999) · 2017
    Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Julie R GaitherYale School of Public Health, Yale University, New Haven, Connecticut; Yale Center for Interdisciplinary Research on AIDS, Yale School of Public Health, Yale University, New Haven, Connecticut. Electronic address: julie.gaither@yale.edu.
Joseph L GouletDepartment of Psychiatry, Yale School of Medicine, Yale University, New Haven, Connecticut; VA Connecticut Healthcare System, West Haven, Connecticut.
William C BeckerVA Connecticut Healthcare System, West Haven, Connecticut; Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.
Stephen CrystalInstitute for Health, Health Care Policy, and Aging Research, Rutgers University, New Brunswick, New Jersey.
E Jennifer EdelmanYale Center for Interdisciplinary Research on AIDS, Yale School of Public Health, Yale University, New Haven, Connecticut; Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.
Kirsha GordonVA Connecticut Healthcare System, West Haven, Connecticut.
Robert D KernsDepartment of Psychiatry, Yale School of Medicine, Yale University, New Haven, Connecticut; VA Connecticut Healthcare System, West Haven, Connecticut.
David RimlandDivision of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia; Atlanta VA Medical Center, Decatur, Georgia.
Melissa SkandersonVA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania.
Daniel F WeisbergDepartment of Internal Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.
Amy C JusticeYale School of Public Health, Yale University, New Haven, Connecticut; Yale Center for Interdisciplinary Research on AIDS, Yale School of Public Health, Yale University, New Haven, Connecticut; VA Connecticut Healthcare System, West Haven, Connecticut; Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.
David A FiellinYale School of Public Health, Yale University, New Haven, Connecticut; Yale Center for Interdisciplinary Research on AIDS, Yale School of Public Health, Yale University, New Haven, Connecticut; Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.

Funding

Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
Alcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
Center for Education and Research on Mental Health TherapeuticsU19HS021112 · AHRQ · RUTGERS, THE STATE UNIV OF N.J. · PI CRYSTAL, STEPHEN · 2011 to 2015
$3.9M
CHAART Consortia Scientific MeetingsU13AA022864 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2014 to 2016
$222k
Chronic Opioid Therapy and Patient Safety in HIV Infected and Uninfected VeteransF31DA035567 · NIDA · YALE UNIVERSITY · PI GAITHER, JULIE ROZELLE · 2013 to 2014
$85k
AHRQ HHS U19HS21112NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U01AA020790NIAAA NIH HHS U10AA013566NIAAA NIH HHS U13 AA022864NIAAA NIH HHS U24 AA020794NIAAA NIH HHS U24AA020794NIDA NIH HHS F31 DA035567NIDA NIH HHS F31DA035567NIMH NIH HHS P30 MH062294NIMH NIH HHS P30MH062294
6 · The paper itself

Abstract

unlabelledWhether patients receive guideline-concordant opioid therapy (OT) is largely unknown and may vary based on provider and patient characteristics. We assessed the extent to which human immunodeficiency virus (HIV)-infected and uninfected patients initiating long-term (≥ 90 days) OT received care concordant with American Pain Society/American Academy of Pain Medicine and Department of Veterans Affairs/Department of Defense guidelines by measuring receipt of 17 indicators during the first 6 months of OT. Of 20,753 patients, HIV-infected patients (n = 6,604) were more likely than uninfected patients to receive a primary care provider visit within 1 month (52.0% vs 30.9%) and 6 months (90.7% vs 73.7%) and urine drug tests within 1 month (14.8% vs 11.5%) and 6 months (19.5% vs 15.4%; all P < .001). HIV-infected patients were also more likely to receive OT concurrent with sedatives (24.6% vs 19.6%) and a current substance use disorder (21.6% vs 17.2%). Among both patient groups, only modest changes in guideline concordance were observed over time: urine drug tests and OT concurrent with current substance use disorders increased, whereas sedative coprescriptions decreased (all Ps for trend < .001). Over a 10-year period, on average, patients received no more than 40% of recommended care. OT guideline-concordant care is rare in primary care, varies by patient/provider characteristics, and has undergone few changes over time. PERSPECTIVE: The promulgation of OT clinical guidelines has not resulted in substantive changes over time in OT management, which falls well short of the standard recommended by leading medical societies. Strategies are needed to increase the provision of OT guideline-concordant care for all patients.

Indexed as

AdultAnalgesics, OpioidChronic PainFemaleGuideline AdherenceHIV InfectionsHumansMalePractice Patterns, Physicians'Primary Health CareUnited StatesVeteransAnalgesics, Opioidchronic painHIVOpioid analgesicspractice guidelinequality of health care

Identifiers

PMID25152300
PMCPMC4253900

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.