ArticleJournal of experimental botany2014
Vitamin C deficiency improves somatic embryo development through distinct gene regulatory networks in Arabidopsis.
Article in Journal of experimental botany, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Balancing tuber vitamin C improvement with trade-off side effect by fine-tuning regulation ofHorticulture research · 2026Article
- Ascorbic acid metabolism and functions.Journal of experimental botany · 2024Article
- A role for ascorbate conjugates of (+)-catechin in proanthocyanidin polymerization.Nature communications · 2022Article
- Weighted Gene Correlation Network Analysis (WGCNA) ofInternational journal of genomics · 2022Article
- Synthetic Strigolactone GR24 ImprovesPlants (Basel, Switzerland) · 2021Article
- Phytochemical Analysis and Establishment of Embryogenic Cell Suspension andPlants (Basel, Switzerland) · 2020Article
- Redox Balance-DDR-miRNA Triangle: Relevance in Genome Stability and Stress Responses in Plants.Frontiers in plant science · 2019Review
- RNA sequencing of Brassica napus reveals cellular redox control of Sclerotinia infection.Journal of experimental botany · 2017Article
- Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.Plant cell reports · 2017Article
- ROS Homeostasis Regulates Somatic Embryogenesis via the Regulation of Auxin Signaling in Cotton.Molecular & cellular proteomics : MCP · 2016Article
- Rice GDP-mannose pyrophosphorylase OsVTC1-1 and OsVTC1-3 play different roles in ascorbic acid synthesis.Plant molecular biology · 2016Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Changes in the endogenous ascorbate redox status through genetic manipulation of cellular ascorbate levels were shown to accelerate cell proliferation during the induction phase and improve maturation of somatic embryos in Arabidopsis. Mutants defective in ascorbate biosynthesis such as vtc2-5 contained ~70 % less cellular ascorbate compared with their wild-type (WT; Columbia-0) counterparts. Depletion of cellular ascorbate accelerated cell division processes and cellular reorganization and improved the number and quality of mature somatic embryos grown in culture by 6-fold compared with WT tissues. To gain insight into the molecular mechanisms underlying somatic embryogenesis (SE), we profiled dynamic changes in the transcriptome and analysed dominant patterns of gene activity in the WT and vtc2-5 lines across the somatic embryo culturing process. Our results provide insight into the gene regulatory networks controlling SE in Arabidopsis based on the association of transcription factors with DNA sequence motifs enriched in biological processes of large co-expressed gene sets. These data provide the first detailed account of temporal changes in the somatic embryo transcriptome starting with the zygotic embryo, through tissue dedifferentiation, and ending with the mature somatic embryo, and impart insight into possible mechanisms for the improved culture of somatic embryos in the vtc2-5 mutant line.
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