ReviewBiochimica et biophysica acta2014
The utility of metabolomics in natural product and biomarker characterization.
Review in Biochimica et biophysica acta, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 78 citations in OpenAlex.
- Volatile Organic Compounds Emitted by Fungi Have Substantial Effects on Growth and Disease Resistance in Arabidopsis thaliana.Plant, cell & environment · 2026Article
- Secondary metabolism ofApplied and environmental microbiology · 2026Review
- Alteration of Metabolic Profile in Patients with Narcolepsy Type 1.Metabolites · 2025Article
- Comprehensive, Quantitative Analysis of SRM 1950: the NIST Human Plasma Reference Material.Analytical chemistry · 2025Article
- Metabolomics and lipidomics signature in celiac disease: a narrative review.Clinical and experimental medicine · 2024Review
- Cytotoxic Isopentenyl Phloroglucinol Compounds fromMetabolites · 2023Article
- Exploring chemical diversity inFrontiers in plant science · 2022Article
- Antifungal Activity againstPlants (Basel, Switzerland) · 2021Article
- Quantitative NMR-Based Biomedical Metabolomics: Current Status and Applications.Molecules (Basel, Switzerland) · 2020Review
- LC-MS-Based Metabolomics for the Chemosystematics of KenyanMolecules (Basel, Switzerland) · 2020Article
- Targeted Isolation of Indole Alkaloids fromMolecules (Basel, Switzerland) · 2020Article
- Unraveling Asian Soybean Rust metabolomics using mass spectrometry and Molecular Networking approach.Scientific reports · 2020Article
- Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach.Natural product reports · 2019Review
- Technologies for the Selection, Culture and Metabolic Profiling of Unique Rhizosphere Microorganisms for Natural Product Discovery.Molecules (Basel, Switzerland) · 2019Article
- Abnormal arachidonic acid metabolic network may reduce sperm motility via P38 MAPK.Open biology · 2019Article
- Time-resolved decoding of metabolic signatures of in vitro growth of the hemibiotrophic pathogen Colletotrichum sublineolum.Scientific reports · 2019Article
- Harnessing the Power of Optical Microscopic and Macroscopic Imaging for Natural Products as Cancer Therapeutics.Frontiers in pharmacology · 2019Review
- Metabolomic Investigations onMarine drugs · 2018Article
- Integration of Biochemometrics and Molecular Networking to Identify Antimicrobials in Angelica keiskei.Planta medica · 2018Article
- A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation.Metabolomics : Official journal of the Metabolomic Society · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMetabolomics is a well-established rapidly developing research field involving quantitative and qualitative metabolite assessment within biological systems. Recent improvements in metabolomics technologies reveal the unequivocal value of metabolomics tools in natural products discovery, gene-function analysis, systems biology and diagnostic platforms. SCOPE OF REVIEW: We review here some of the prominent metabolomics methodologies employed in data acquisition and analysis of natural products and disease-related biomarkers. MAJOR
conclusionsThis review demonstrates that metabolomics represents a highly adaptable technology with diverse applications ranging from environmental toxicology to disease diagnosis. Metabolomic analysis is shown to provide a unique snapshot of the functional genetic status of an organism by examining its biochemical profile, with relevance toward resolving phylogenetic associations involving horizontal gene transfer and distinguishing subgroups of genera possessing high genetic homology, as well as an increasing role in both elucidating biosynthetic transformations of natural products and detecting preclinical biomarkers of numerous disease states. GENERAL SIGNIFICANCE: This review expands the interest in multiplatform combinatorial metabolomic analysis. The applications reviewed range from phylogenetic assignment, biosynthetic transformations of natural products, and the detection of preclinical biomarkers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.