ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2014
The Israel Diabetes and Cognitive Decline (IDCD) study: Design and baseline characteristics.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Combination of Intranasal Insulin With Oral Semaglutide to Improve Cognition and Cerebral Blood Flow: a Feasibility Study
Cognitive-motor Intervention Using Virtual Reality for Middle-aged Individuals at High Dementia Risk
Who cites it
41 citing papers in PubMed.
- Computerized Cognitive Training for Older Adults at Higher Dementia Risk due to Diabetes: Findings From a Randomized Controlled Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020 · on this mapTrial
- Ethnicity predicts long-term depressive symptom patterns in older adults with type 2 diabetes.International psychogeriatrics · 2025Article
- Emotional response to amyloid beta status disclosure among research participants at high dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Cognitive decline in older adults with type 2 diabetes: Unraveling site-specific glycoproteomic alterations.PloS one · 2025Article
- Amyloid deposition and small vessel disease are associated with cognitive function in older adults with type 2 diabetes.Scientific reports · 2024Article
- Poor self-rated health is associated with faster cognitive decline and greater small vessel disease in older adults with type 2 diabetes.Diabetes/metabolism research and reviews · 2024Article
- Exendin-4 ameliorates tau hyperphosphorylation and cognitive impairment in type 2 diabetes through acting on Wnt/β-catenin/NeuroD1 pathway.Molecular medicine (Cambridge, Mass.) · 2023Article
- Decrease in Gait Speed Over Time Is Associated With Increase in Number of Depression Symptoms in Older Adults With Type 2 Diabetes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- A feasibility study of the combination of intranasal insulin with dulaglutide for cognition in older adults with metabolic syndrome at high dementia risk - Study rationale and design.Mechanisms of ageing and development · 2023Article
- Consumption of Ultra-Processed Food and Cognitive Decline among Older Adults With Type-2 Diabetes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Physical Activity Is Associated with Slower Cognitive Decline in Older Adults with Type 2 Diabetes.The journal of prevention of Alzheimer's disease · 2023Article
- Stability in BMI over time is associated with a better cognitive trajectory in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Greater intake of the MEDI diet is associated with better cognitive trajectory in older adults with type 2 diabetes.Diabetes research and clinical practice · 2022Observational
- Article
- Alzheimer's Disease Polygenic Risk Score Is Not Associated With Cognitive Decline Among Older Adults With Type 2 Diabetes.Frontiers in aging neuroscience · 2022Article
- Specific depression dimensions are associated with a faster rate of cognitive decline in older adults.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Trajectories of depression symptoms over time differ by APOE4 genotype in older adults with type 2 diabetes.International journal of geriatric psychiatry · 2021Article
- Specific Dimensions of Depression Have Different Associations With Cognitive Decline in Older Adults With Type 2 Diabetes.Diabetes care · 2021Article
- Design and Feasibility of a Randomized Controlled Pilot Trial to Reduce Exposure and Cognitive Risk Associated With Advanced Glycation End Products in Older Adults With Type 2 Diabetes.Frontiers in nutrition · 2021Article
- Increase in Number of Depression Symptoms Over Time is Related to Worse Cognitive Outcomes in Older Adults With Type 2 Diabetes.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundType 2 diabetes (T2D) is associated with increased risk of dementia. The prospective longitudinal Israel Diabetes and Cognitive Decline study aims at identifying T2D-related characteristics associated with cognitive decline.
methodsSubjects are population-based T2D 65+, initially cognitively intact. Medical conditions, blood examinations, and medication use data are since 1998; cognitive, functional, demographic, psychiatric, DNA, and inflammatory marker study assessments were conducted every 18 months. Because the duration of T2D reflects its chronicity and implications, we compared short (0-4.99 years), moderate (5-9.99), and long (10+) duration for the first 897 subjects.
resultsThe long duration group used more T2D medications, had higher glucose, lower glomerular filtration rate, slower walking speed, and poorer cognitive functioning. Duration was not associated with most medical, blood, urine, and vital characteristics.
conclusionsTracking cognition, with face-to-face evaluations, exploiting 15 years of historical detailed computerized, easily accessible, and validated T2D-related characteristics may provide novel insights into T2D-related dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.