Evidence map›Paper›PMID 25150579›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2014

Beta2-adrenoceptor stimulation has no effect on skeletal muscle glucose uptake.

A H Mulder, P Smits, C J Tack

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

A H MulderDepartment of Internal Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
P Smits
C J Tack
Radboud University Medical Center · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBlockade of the β-adrenergic receptor induces insulin resistance and chronic β-adrenoceptor stimulation improves insulin sensitivity in animals. We tested whether acute β2-adrenoceptor stimulation increased insulin-induced glucose uptake in human forearm skeletal muscle. MATERIALS AND

methodsDuring a hyperinsulinemic euglycemic clamp procedure, forearm glucose uptake was calculated by multiplying the arteriovenous glucose gradient and forearm blood flow before and during local infusion of the β2-adrenoceptor salbutamol into the brachial artery.

conclusionsβ2-Adrenergic stimulation had no effect on insulin-stimulated glucose uptake in human forearm skeletal muscle.

Indexed as

Adrenergic beta-2 Receptor AgonistsAdultAlbuterolExerciseFemaleGlucoseGlucose Clamp TechniqueHumansHypoglycemic AgentsInsulinMaleMuscle ContractionMuscle, SkeletalYoung AdultAdrenergic beta-2 Receptor AgonistsAlbuterolGlucoseHypoglycemic AgentsInsulin

Identifiers

PMID25150579
OpenAlexW2081071012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.