ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2014
Toxins induce 'malaise' behaviour in the honeybee (Apis mellifera).
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 86 citations in OpenAlex.
- Article
- Young honey bees Apis mellifera learn to avoid pollen contaminated with glyphosate or imidacloprid.Scientific reports · 2026Article
- Visual learning performance in free-flying honey bees is independent of sucrose and light responsiveness and depends on training context.Scientific reports · 2026Article
- Behavioral and molecular disruptions in honey bees induced by lithium chloride exposure.Scientific reports · 2025Article
- Toxic bait abandonment by an invasive ant is driven by aversive memories.Communications biology · 2025Article
- Article
- Ants evade harmful food by active abandonment.Communications biology · 2024Article
- Mouthparts of the bumblebee (eLife · 2023Article
- Effects of lithium on locomotor activity and circadian rhythm of honey bees.Scientific reports · 2023Article
- Review: the risks of spray adjuvants to honey bees.Journal of insect science (Online) · 2023Review
- Gravisensation and modulation of gravitactic responses by other sensory cues in the monarch butterfly (Danaus plexippus).The Journal of experimental biology · 2023Article
- Article
- Poison or Potion: Effects of Sunflower Phenolamides on Bumble Bees and Their Gut Parasite.Biology · 2022Article
- Article
- LC-MS/MS Quantification Reveals Ample Gut Uptake and Metabolization of Dietary Phytochemicals in Honey Bees (Journal of agricultural and food chemistry · 2021Article
- Article
- Sublethal effects of chronic exposure to CdO or PbO nanoparticles or their binary mixture on the honey bee (Apis millefera L.).Environmental science and pollution research international · 2020Article
- Acute sublethal exposure to toxic heavy metals alters honey bee (Apis mellifera) feeding behavior.Scientific reports · 2019Article
- Stressful conditions reveal decrease in size, modification of shape but relatively stable asymmetry in bumblebee wings.Scientific reports · 2018Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
To avoid poisoning and death when toxins are ingested, the body responds with a suite of physiological detoxification mechanisms accompanied by behaviours that in mammals often include vomiting, nausea, and lethargy. Few studies have characterised whether insects exhibit characteristic 'malaise-like' behaviours in response to intoxication. Here, we used the honeybee to investigate how intoxication produced by injection or ingestion with three toxins with different pharmacological modes of action quinine, amygdalin, and lithium chloride affected behaviour. We found that toxin-induced changes in behaviour were best characterised by more time spent grooming. Bees also had difficulty performing the righting reflex and exhibited specific toxin-induced behaviours such as abdomen dragging and curling up. The expression of these behaviours also depended on whether a toxin had been injected or ingested. When toxins were ingested, they were least 10 times less concentrated in the haemolymph than in the ingested food, suggesting that their absorption through the gut is strongly regulated. Our data show that bees exhibit changes in behaviour that are characteristic of 'malaise' and suggest that physiological signalling of toxicosis is accomplished by multiple post-ingestive pathways in animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.