ArticleProceedings of the National Academy of Sciences of the United States of America2014
Transmission of a signal that synchronizes cell movements in swarms of Myxococcus xanthus.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Large-Scale Vortices with Dynamic Rotation Emerged from Monolayer Collective Motion of GlidingJournal of bacteriology · 2021Article
- Topological defects promote layer formation inNature physics · 2021Article
- Article
- The Less Expensive Choice: Bacterial Strategies to Achieve Successful and Sustainable Reciprocal Interactions.Frontiers in microbiology · 2020Review
- Article
- Myxobacteria: Moving, Killing, Feeding, and Surviving Together.Frontiers in microbiology · 2016Review
- How Myxobacteria Cooperate.Journal of molecular biology · 2015Review
- Directional reversals enable Myxococcus xanthus cells to produce collective one-dimensional streams during fruiting-body formation.Journal of the Royal Society, Interface · 2015Article
- The cognitive cell: bacterial behavior reconsidered.Frontiers in microbiology · 2015Review
- A genetic screen in Myxococcus xanthus identifies mutants that uncouple outer membrane exchange from a downstream cellular response.Journal of bacteriology · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
We offer evidence for a signal that synchronizes the behavior of hundreds of Myxococcus xanthus cells in a growing swarm. Swarms are driven to expand by the periodic reversing of direction by members. By using time-lapse photomicroscopy, two organized multicellular elements of the swarm were analyzed: single-layered, rectangular rafts and round, multilayered mounds. Rafts of hundreds of cells with their long axes aligned in parallel enlarge as individual cells from the neighborhood join them from either side. Rafts can also add a second layer piece by piece. By repeating layer additions to a raft and rounding each layer, a regular multilayered mound can be formed. About an hour after a five-layered mound had formed, all of the cells from its top layer descended to the periphery of the fourth layer, both rapidly and synchronously. Following the first synchronized descent and spaced at constant time intervals, a new fifth layer was (re)constructed from fourth-layer cells, in very close proximity to its old position and with a number of cells similar to that before the "explosive" descent. This unexpected series of changes in mound structure can be explained by the spread of a signal that synchronizes the reversals of large groups of individual cells.
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