Evidence map›Paper›PMID 25149307›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2014

Intravital imaging of cytotoxic T lymphocytes.

Gaetano Faleo, Per-Olof Berggren, Antonello Pileggi

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. IntraocularMolecular metabolism · 2017
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gaetano FaleoTransplantation Research Laboratory, Department of Surgery, University of California, 513 Parnassus Ave., HSE-520, San Francisco, CA, 94143, USA, Gaetano.Faleo@ucsfmedctr.org.
Per-Olof Berggren
Antonello Pileggi

Funding

Virginia Mason/UCHSC Autoimmune Prevention CenterU19AI050864 · NIAID · UNIVERSITY OF COLORADO DENVER · PI EISENBARTH, GEORGE S · 2001 to 2011
$29.2M
ISLET CELL RESOURCE FOR DIABETES RESEARCH AND TREATMENTU42RR016603 · NCRR · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RICORDI, CAMILLO · 2001 to 2009
$7.8M
Multi-Disciplinary Approaches to Driving Therapeutic Human Beta Cell ReplicationU01DK089538 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEWART, ANDREW F. · 2010 to 2014
$3.6M
Insulin Producing Cells from Amniotic Stem Cells for Diabetes TherapyR01EB008009 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ATALA, ANTHONY · 2007 to 2009
$3.3M
The Role of Innervation for Hormone Secretion in Human IsletsR01DK084321 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CAICEDO, ALEJANDRO · 2011 to 2015
$1.8M
Studies in Translational Regenerative MedicineT32EB014836 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ANTHONY ATALA, Victoria Weis · 2013 to 2026
$1.7M
The Role of Innervation for Hormone Secretion in Human IsletsR56DK084321 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CAICEDO, ALEJANDRO · 2009 to 2016
$306k
Glutamate Signaling in Human Islets of LangerhansR03DK075487 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CAICEDO VIERKANT, ALEJANDRO · 2006 to 2007
$301k
Noninvasive two-photon imaging of pancreatic islet graft rejection in the eyeF32DK083226 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ABDULREDA, MIDHAT H · 2009 to 2011
$151k
NCRR NIH HHS 5U42 RR016603NCRR NIH HHS U42 RR016603NIAID NIH HHS 5U19AI050864-10NIAID NIH HHS U19 AI050864NIBIB NIH HHS 1R01EB008009NIBIB NIH HHS R01 EB008009NIBIB NIH HHS T32 EB014836NIDDK NIH HHS F32 DK083226NIDDK NIH HHS F32DK083226NIDDK NIH HHS R01 DK084321NIDDK NIH HHS R01DK084321NIDDK NIH HHS R03 DK075487NIDDK NIH HHS R03DK075487NIDDK NIH HHS R56 DK084321NIDDK NIH HHS R56DK084321NIDDK NIH HHS U01 DK089538NIDDK NIH HHS U01DK089538
6 · The paper itself

Abstract

Intravital imaging approaches are proving to be essential to address new questions to better understand how the immune system operates. These approaches are especially valuable to characterize the complex organization of immune responses in vivo. Here, we examine how to take advantage of the cornea as a natural body window to apply noninvasive imaging techniques to assess cytotoxic T lymphocyte involvement in the immune rejection process in a model of intraocular allogeneic islet transplantation.

Indexed as

AnimalsAnterior ChamberCorneaCytotoxicity, ImmunologicGraft RejectionIslets of Langerhans TransplantationMiceMice, Inbred DBAMicroscopyT-Lymphocytes, CytotoxicTransplantation, Homologous

Identifiers

PMID25149307
PMCPMC8855369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.