ArticleJournal of neuro-oncology2014
Risk factors for venous thromboembolism in patients undergoing craniotomy for neoplastic disease.
Article in Journal of neuro-oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Development and validation of a multi-parameter nomogram for venous thromboembolism in patients undergoing surgery for brain tumors: a retrospective analysis.Neurosurgical review · 2025Article
- Predictive nomogram for postoperative lower-limb deep vein thrombosis in patients undergoing endoscopic endonasal surgery during hospitalization: a retrospective cohort study.Scientific reports · 2025Article
- The Role of Injectables in the Treatment and Prevention of Cancer-Associated Thrombosis.Cancers · 2023Review
- Epidemiology, biology, and management of venous thromboembolism in gliomas: An interdisciplinary review.Neuro-oncology · 2023Article
- A Retrospective Comparative Cohort Study of Craniotomy and Prophylactic Enoxaparin Timing.Cureus · 2022Article
- Venous thromboembolic and hemorrhagic events after meningioma surgery: A single-center retrospective cohort study of risk factors.PloS one · 2022Article
- Impaired contraction of blood clots precedes and predicts postoperative venous thromboembolism.Scientific reports · 2020Article
- Venous Thromboembolism in Patients With Brain Cancer: Focus on Prophylaxis and Management.Cureus · 2020Review
- Risk Factors and Clinical Significance of D-Dimer in the Development of Postoperative Venous Thrombosis in Patients with Lung Tumor.Cancer management and research · 2020Article
- Patterns of seizure prophylaxis after oncologic neurosurgery.Journal of neuro-oncology · 2020Article
- Venous thromboembolism in children undergoing surgery: incidence, risk factors and related adverse events.World journal of pediatric surgery · 2020Article
- Adverse Events After Microvascular Decompression: A National Surgical Quality Improvement Program Analysis.World neurosurgery · 2019Article
- Predictors of Venous Thromboembolism After Nonemergent Craniotomy: A Nationwide Readmission Database Analysis.World neurosurgery · 2019Article
- Platelet activation parameters and platelet-leucocyte-conjugate formation in glioblastoma multiforme patients.Oncotarget · 2018Article
- Venous thromboembolism and intracranial hemorrhage after craniotomy for primary malignant brain tumors: a National Surgical Quality Improvement Program analysis.Journal of neuro-oncology · 2018Article
- Thirty-Day Morbidity Associated with Pelvic Fixation in Adult Patients Undergoing Fusion for Spinal Deformity: A Propensity-Matched Analysis.Global spine journal · 2017Article
- Impact of operative length on post-operative complications in meningioma surgery: a NSQIP analysis.Journal of neuro-oncology · 2017Article
- Silent pulmonary thromboembolism in neurosurgery patients: Report of 2 cases and literature review.Medicine · 2016Review
- Risk of Venous Thromboembolism in Patients with Large Hemispheric Infarction Undergoing Decompressive Hemicraniectomy.Neurocritical care · 2016Article
- Predictive Model of Risk Factors for Secondary Venous Thromboembolism in Patients After Craniotomy.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients undergoing neurosurgical procedures for neoplasia have historically been considered at higher risk for developing venous thromboembolism (VTE). We sought to identify risk factors associated with VTE in patients undergoing craniotomy for tumor resection. We reviewed a national surgical quality database (American College of Surgeons National Surgical Quality Improvement Project, ACS-NSQIP, http://site.acsnsqip.org/ ). Patients undergoing non-emergent craniotomy for neoplastic indications were identified based on current procedural terminology codes. Clinical factors were identified that were associated with VTE events. 3,098 patients who underwent non-emergent craniotomy were identified. 1,741 patients underwent procedures for neoplastic disease (56.2 %). The rate of DVT in these patients was 3.2 % compared to 1.4 % in other neurosurgical patients (OR 2.30, CI 2.29-2.30). The rate of pulmonary embolism was 1.8 % compared to 0.5 % (OR 3.61, CI 3.60-3.62). Univariate analysis identified several factors correlated with VTE. Pre-operative characteristics associated with VTE were the presence of impaired sensorium, dependent functional status, and age > 60 years. Total operative time > 4 h was associated with VTE. Post-operative events associated with VTE included pneumonia, unplanned intubation, fail to wean from ventilator, UTI, stroke, sepsis and septic shock. Age > 60, OR time > 4 h, UTI, and septic shock were significantly associated with VTE in multivariate analysis. Patients undergoing craniotomy for neoplasm are at increased risk of VTE. This risk appears to be modified by pre-operative medical comorbidities, longer operative time, and post-operative complications.
Indexed as
Identifiers
25149164What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.