Evidence map›Paper›PMID 25148902›Full record

SynthesisBMC cancer2014

Fast-track surgery versus traditional perioperative care in laparoscopic colorectal cancer surgery: a meta-analysis.

Jun-Hua Zhao, Jing-Xu Sun, Peng Gao, Xiao-Wan Chen, Yong-Xi Song, Xuan-Zhang Huang, Hui-Mian Xu, Zhen-Ning Wang

Registry-linked trialOpen access · goldAbstract readComparative StudyMeta-Analysis
In one paragraph

Synthesis in BMC cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04378465 (Enhanced Recovery Program in Laparoscopic Colorectal Surgery), which is not on this map. Cited by 24 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 7 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04378465 completednot on this map

Enhanced Recovery Program in Laparoscopic Colorectal Surgery: an Observational Controlled Trial

TypeobservationalSponsorUniversity Hospital of FerraraRan2013 to 2019Enrolled200ConditionsColorectal Surgery, Recovery of FunctionArmsEnhanced Recovery Program (ERP)
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 7 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Pooled it
  6. Is the Enhanced Recovery After Surgery (ERAS) Program Effective and Safe in Laparoscopic Colorectal Cancer Surgery? A Meta-Analysis of Randomized Controlled Trials.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
    Pooled it
  7. Pooled it
  8. Article
  9. Review
  10. Management of Patients with Colorectal Cancer through Fast-Track Surgery.International journal of environmental research and public health · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Before-and-After Study of the First Four Years of the Enhanced Recovery after Surgery (ERASInternational journal of environmental research and public health · 2022
    Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Bioactive constituents isolated fromJournal of experimental pharmacology · 2018
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jun-Hua Zhao
Jing-Xu Sun
Peng Gao
Xiao-Wan Chen
Yong-Xi Song
Xuan-Zhang Huang
Hui-Mian Xu
Zhen-Ning WangDepartment of Surgical Oncology and General Surgery, the First Hospital of China Medical University, Shenyang 110001, People's Republic of China. josieon826@sina.cn.
China Medical University · CNFirst Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth laparoscopic and fast-track surgery (FTS) have shown some advantages in colorectal surgery. However, the effectiveness of using both methods together is unclear. We performed this meta-analysis to compare the effects of FTS with those of traditional perioperative care in laparoscopic colorectal cancer surgery.

methodsWe searched the PubMed, EMBASE, Cochrane Library, and Ovid databases for eligible studies until April 2014. The main end points were the duration of the postoperative hospital stay, time to first flatus after surgery, time of first bowel movement, total postoperative complication rate, readmission rate, and mortality.

resultsFive randomized controlled trials and 5 clinical controlled trials with 1,317 patients were eligible for analysis. The duration of the postoperative hospital stay (weighted mean difference [WMD], -1.64 days; 95% confidence interval [CI], -2.25 to -1.03; p < 0.001), time to first flatus (WMD, -0.40 day; 95% CI, -0.77 to -0.04; p = 0.03), time of first bowel movement (WMD, -0.98 day; 95% CI, -1.45 to -0.52; p < 0.001), and total postoperative complication rate (risk ratio [RR], 0.67; 95% CI, 0.56-0.80; p < 0.001) were significantly reduced in the FTS group. No significant differences were noted in the readmission rate (RR, 0.64; 95% CI, 0.41-1.01; p = 0.06) or mortality (RR, 1.55; 95% CI, 0.42-5.71; p = 0.51).

conclusionAmong patients undergoing laparoscopic colorectal cancer surgery, FTS is associated with a significantly shorter postoperative hospital stay, more rapid postoperative recovery, and, notably, greater safety than is expected from traditional care.

Indexed as

AdultAgedAged, 80 and overClinical Trials as TopicColorectal NeoplasmsColorectal SurgeryDatabases, BibliographicHumansLaparoscopyLength of StayMaleMiddle AgedPerioperative CareRecovery of Function

Identifiers

PMID25148902
PMCPMC4161840
OpenAlexW1990736025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.