Evidence map›Paper›PMID 25148361›Full record

ArticlePloS one2014

Accuracy of the interpretation of chest radiographs for the diagnosis of paediatric pneumonia.

Mohamed A Elemraid, Michelle Muller, David A Spencer, Stephen P Rushton, Russell Gorton, Matthew F Thomas, Katherine M Eastham, Fiona Hampton, Andrew R Gennery, Julia E Clark and 1 more

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Diagnostic accuracy of various imaging modalities for children with pneumonia: a systematic review and network meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohamed A ElemraidDepartment of Paediatric Infectious Disease and Immunology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Michelle MullerDepartment of Radiology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
David A SpencerDepartment of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
Stephen P RushtonBiological, Clinical and Environmental Systems Modelling Group, School of Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Russell GortonRegional Epidemiology Unit, Public Health England North East, Newcastle upon Tyne, United Kingdom.
Matthew F ThomasDepartment of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Biological, Clinical and Environmental Systems Modelling Group, School of Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Katherine M EasthamDepartment of Paediatrics, Sunderland Royal Hospital, Sunderland, United Kingdom.
Fiona HamptonDepartment of Paediatrics, James Cook University Hospital, Middlesbrough, United Kingdom.
Andrew R GenneryDepartment of Paediatric Infectious Disease and Immunology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Julia E ClarkDepartment of Paediatric Infectious Disease, Royal Children's Hospital, Brisbane, Queensland, Australia.
North East of England Paediatric Respiratory Infection Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWorld Health Organization (WHO) radiological classification remains an important entry criterion in epidemiological studies of pneumonia in children. We report inter-observer variability in the interpretation of 169 chest radiographs in children suspected of having pneumonia.

methodsAn 18-month prospective aetiological study of pneumonia was undertaken in Northern England. Chest radiographs were performed on eligible children aged ≤16 years with clinical features of pneumonia. The initial radiology report was compared with a subsequent assessment by a consultant cardiothoracic radiologist. Chest radiographic changes were categorised according to the WHO classification.

resultsThere was significant disagreement (22%) between the first and second reports (kappa = 0.70, P<0.001), notably in those aged <5 years (26%, kappa = 0.66, P<0.001). The most frequent sources of disagreement were the reporting of patchy and perihilar changes.

conclusionThis substantial inter-observer variability highlights the need for experts from different countries to create a consensus to review the radiological definition of pneumonia in children.

Indexed as

Observer VariationRadiography, ThoracicAdolescentChildChild, PreschoolEnglandFemaleHumansInfantMalePneumoniaProspective StudiesWorld Health Organization

Identifiers

PMID25148361
PMCPMC4141860

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.