Evidence map›Paper›PMID 25148158›Full record

ReviewAJR. American journal of roentgenology2014

Insights into quantitative diffusion-weighted MRI for musculoskeletal tumor imaging.

Ty K Subhawong, Michael A Jacobs, Laura M Fayad

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in AJR. American journal of roentgenology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05079997 (Role of MAGNETIC RESONANCE IMAGING in Characterization of Superficial Soft Tissue Masses), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05079997 unknown statusnot on this mapstarted 2021, after this paper: background citation

Role of MAGNETIC RESONANCE IMAGING in Characterization of Superficial Soft Tissue Masses

TypeobservationalSponsorAssiut UniversityRan2021 to 2023Enrolled50ConditionsSoft Tissue MassesArmsMAGNETIC RESONANCE IMAGING
3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using HyperpolarizedAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Bone tumors: state-of-the-art imaging.Skeletal radiology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ty K Subhawong1 Department of Radiology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
Michael A Jacobs
Laura M Fayad

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
Theranostic Imaging of Metastatic Prostate CancerP50CA103175 · NCI · JOHNS HOPKINS UNIVERSITY · PI BHUJWALLA, ZAVER M. · 2003 to 2015
$17.9M
PHASE I TRIALS OF ANTICANCER AGENTSU01CA070095 · NCI · JOHNS HOPKINS UNIVERSITY · PI CARDUCCI, MICHAEL A · 1995 to 2013
$8.6M
Multi-Modality Quantitiative Imaging for Evaluation of Response to Cancer TherapyU01CA140204 · NCI · JOHNS HOPKINS UNIVERSITY · PI DU, YONG, SOLNES, LILJA · 2011 to 2022
$6.1M
Cytotoxicity of MLN4924 in Acute Myeloid LeukemiaF30CA183507 · NCI · MAYO CLINIC ROCHESTER · PI KNORR, KATHERINE LORRAINE BROIN · 2014 to 2017
$149k
NCI NIH HHS 5P30CA006973NCI NIH HHS P50CA103175NCI NIH HHS U01CA070095NCI NIH HHS U01CA140204
6 · The paper itself

Abstract

objectiveThe purposes of this article are to discuss the technical considerations for performing quantitative diffusion-weighted MRI (DWI) with apparent diffusion coefficient (ADC) mapping, examine the role of DWI in whole-body MRI, and review how DWI with ADC mapping can serve as an adjunct to information gleaned from conventional MRI in the radiologic evaluation of musculoskeletal lesions.

conclusionThe primary role of whole-body DWI is in tumor detection; localized DWI is helpful in differentiating malignant bone and soft-tissue lesions. After treatment, an increase in tumor ADC values correlates with response to cytotoxic therapy. The use of DWI in the evaluation of musculoskeletal lesions requires knowledge of potential diagnostic pitfalls that stem from technical challenges and confounding biochemical factors that influence ADC maps but are unrelated to lesion cellularity.

Indexed as

AdultAgedBone NeoplasmsDiffusion Magnetic Resonance ImagingFemaleHumansImage EnhancementImaging, Three-DimensionalJoint DiseasesMaleMiddle AgedMuscle NeoplasmsWhole Body Imagingbone tumordiffusion-weighted imagingMRIneoplasmsoft-tissue tumor

Identifiers

PMID25148158

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.