Evidence map›Paper›PMID 25147720›Full record

ArticleJundishapur journal of microbiology2014

Genetic elements associated with antimicrobial resistance among intestinal bacteria.

Bita Bakhshi, Nazanin Eftekhari, Mohammad Reza Pourshafie

Open access · hybridAbstract read
In one paragraph

Article in Jundishapur journal of microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Prevalence of fluoroquinolone-resistantPathogens and global health · 2020
    Pooled it
  2. Resistance ofFrontiers in pharmacology · 2023
    Review
  3. Review
  4. Article
  5. An overview of diarrheagenicJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Bita BakhshiDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, IR Iran.
Nazanin EftekhariDepartment of Biology, Faculty of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, IR Iran.
Mohammad Reza PourshafieDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, IR Iran.
Islamic Azad University, Science and Research Branch · IRPasteur Institute of Iran · IRTarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntegrons are the major reasons of multidrug resistance (MDR) among enteropathogenic bacteria. Occurrence of horizontal gene transfer between integron-carrying microorganisms and other enteric bacteria may increase the rate of emergence of integron-associated antibiotic resistance.

objectivesThe objective of this study was to investigate class 1 integrons among members of enteropathogenic bacteria isolated from patients in Iran. MATERIALS AND

methodsA total of 120 enteropathogenic bacterial isolates from diarrhoeal patients were included in this study. Identities of the isolates were investigated by biochemical tests and confirmed by genus or species specific PCRs. Antimicrobial susceptibility testing was performed according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. Presence of class 1 integron among the isolates was investigated using primers specific for the integrase gene conserved region.

resultsThe result of this study showed the highest resistance to trimethoprim and cotrimoxazole, especially in enteropathogenic Escherichia coli (EPEC) (100%), Shigella sonnei (93.7%) and Vibrio cholerae (95%). The results showed that 16 (57.1%) of the 28 EPEC, 9 (25%) of the 36 Salmonella enterica, 32 of the 13 (40.6%) Sh. sonnei, and only 1 (4.2%) of the 24 V. cholerae isolate harbored class 1 integron.

conclusionsThe data obtained in the present study suggested that class 1 integrons are widely distributed among members of Enterobacteriaceae. The resistance patterns of our E. coli, S. sonnei, and S. enterica isolates were nearly identical, suggesting the same genetic elements involved in attainment of multi-drug resistance.

Indexed as

Antimicrobial AgentsDrug ResistanceIntegronsIntestinal Bacteria

Identifiers

PMID25147720
PMCPMC4138638
OpenAlexW2163245571

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.