Evidence map›Paper›PMID 25147255›Full record

ArticleDiabetes care2014

Birth weight and risk of type 2 diabetes in the black women's health study: does adult BMI play a mediating role?

Edward A Ruiz-Narváez, Julie R Palmer, Hanna Gerlovin, Lauren A Wise, Varsha G Vimalananda, James L Rosenzweig, Lynn Rosenberg

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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  17. Birthweight and cardiometabolic risk patterns in multiracial children.International journal of obesity (2005) · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Edward A Ruiz-NarváezSlone Epidemiology Center at Boston University, Boston, MA Department of Epidemiology, Boston University School of Public Health, Boston, MA eruiznar@bu.edu.
Julie R PalmerSlone Epidemiology Center at Boston University, Boston, MA Department of Epidemiology, Boston University School of Public Health, Boston, MA.
Hanna GerlovinSlone Epidemiology Center at Boston University, Boston, MA Department of Biostatistics, Boston University School of Public Health, Boston, MA.
Lauren A WiseSlone Epidemiology Center at Boston University, Boston, MA Department of Epidemiology, Boston University School of Public Health, Boston, MA.
Varsha G VimalanandaSection of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, MA.
James L RosenzweigSection of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, MA.
Lynn RosenbergSlone Epidemiology Center at Boston University, Boston, MA Department of Epidemiology, Boston University School of Public Health, Boston, MA.
Boston University · US

Funding

FOLLOW-UP STUDY FOR CAUSES OF ILLNESS IN BLACK WOMENR01CA058420 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 1999 to 2013
$20.7M
A Follow-up Study for Causes of Cancer in Black WomenUM1CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 2012 to 2017
$13.7M
Weight gain, type 2 diabetes, and factors that affect neuroendocrine functionR01MD007015 · NIMHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 2012 to 2016
$1.4M
NCI NIH HHS R01 CA058420NCI NIH HHS R01-CA-058420NCI NIH HHS UM1 CA164974NCI NIH HHS UM1-CA-164974NIMHD NIH HHS R01 MD007015NIMHD NIH HHS R01-MD-007015
6 · The paper itself

Abstract

objectiveTo assess the association of birth weight with incident type 2 diabetes, and the possible mediating influence of obesity, in a large cohort of U.S. black women. RESEARCH DESIGN AND

methodsThe Black Women's Health Study is an ongoing prospective study. We used Cox proportional hazards models to estimate incidence rate ratios (IRRs) and 95% CI for categories of birth weight (very low birth weight [<1,500 g], low birth weight [1,500-2,499 g], and high birth weight [≥4,000 g]) in reference to normal birth weight (2,500-3,999 g). Models were adjusted for age, questionnaire cycle, family history of diabetes, caloric intake, preterm birth, physical activity, years of education, and neighborhood socioeconomic status with and without inclusion of terms for adult BMI.

resultsWe followed 21,624 women over 16 years of follow-up. There were 2,388 cases of incident diabetes. Women with very low birth weight had a 40% higher risk of disease (IRR 1.40 [95% CI 1.08-1.82]) than women with normal birth weight; women with low birth weight had a 13% higher risk (IRR 1.13 [95% CI 1.02-1.25]). Adjustment for BMI did not appreciably change the estimates.

conclusionsVery low birth weight and low birth weight appear to be associated with increased risk of type 2 diabetes in African American women, and the association does not seem to be mediated through BMI. The prevalence of low birth weight is especially high in African American populations, and this may explain in part the higher occurrence of type 2 diabetes.

Indexed as

Birth WeightBody Mass IndexAdultAgedBlack or African AmericanDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansMiddle AgedObesityProspective StudiesRisk FactorsSurveys and QuestionnairesUnited StatesWomen's Health

Identifiers

PMID25147255
PMCPMC4140161
OpenAlexW2094752343

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.