SynthesisAJNR. American journal of neuroradiology2014
Cavernous carotid aneurysms in the era of flow diversion: a need to revisit treatment paradigms.
Synthesis in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Natural history and treatment of asymptomatic unruptured carotid cavernous aneurysms: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Pipeline Embolization device for the treatment of unruptured intracranial saccular aneurysms: a systematic review and meta-analysis of long-term outcomes.Neurosurgical review · 2024Pooled it
- Flow diversion for compressive unruptured internal carotid artery aneurysms with neuro-ophthalmological symptoms: a systematic review and meta-analysis.Journal of neurointerventional surgery · 2023Pooled it
- Endoluminal flow diverters in the treatment of sidewall and bifurcation aneurysm: A systematic review and meta-analysis of complications and angiographic outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022Pooled it
- Flow Diversion in Ruptured Intracranial Aneurysms: A Meta-Analysis.AJNR. American journal of neuroradiology · 2017Pooled it
- Delayed Rupture Presenting as Direct Carotid-Cavernous Fistula after Flow Diversion for a Cavernous Internal Carotid Artery Aneurysm with Enlarging Blebs: A Case Report.Journal of neuroendovascular therapy · 2026Article
- High-flow bypass surgery for a large cavernous internal carotid artery aneurysm associated with persistent primitive trigeminal artery: A case report.Surgical neurology international · 2026Article
- Onset-to-treatment time and aneurysmal regression predict improvement of cranial neuropathy after flow diversion treatment in patients with symptomatic internal carotid artery aneurysms.Journal of neurointerventional surgery · 2023Article
- Prediction of atherosclerotic changes in cavernous carotid aneurysms based on computational fluid dynamics analysis: a proof-of-concept study.Neuroradiology · 2022Article
- Endovascular treatment of cavernous carotid artery aneurysms: A 10-year, single-center experience.The neuroradiology journal · 2021Article
- Use of flow diverter stent for treatment of a cervical carotid artery dissection and pseudoaneurysm causing Horner's syndrome.BMJ case reports · 2021Article
- Article
- Trans-Cell Technique through Mesh of Pipeline Embolization Device: A Case Report.Journal of neuroendovascular therapy · 2021Article
- Cavernous carotid artery large aneurysm treated with a new flow diverter - Xcalibur aneurysm occlusion device (AOD).Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020Article
- The Evolution of Flow-Diverting Stents for Cerebral Aneurysms; Historical Review, Modern Application, Complications, and Future Direction.Journal of Korean Neurosurgical Society · 2020Article
- Concomitant occurrence of clinoid and cavernous segment aneurysms complicated with carotid cavernous fistula: A case report.Medicine · 2019Article
- Therapeutic Internal Carotid Artery Occlusion for Large and Giant Aneurysms: A Single Center Cohort of 146 Patients.AJNR. American journal of neuroradiology · 2016Observational
- Visual Outcomes after Surgery for Paraclinoid Aneurysms: A Fujita Experience.Asian journal of neurosurgeryArticle
- Atypical Symptomatic Bilateral Spontaneous Cavernous Carotid Aneurysm with Systemic Vessel Wall Pathology in Young Female: A Rare Case Report.Asian journal of neurosurgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeRecent techniques of endoluminal reconstruction with flow-diverting stents have not been incorporated into treatment algorithms for cavernous carotid aneurysms. This study examines the authors' institutional experience and a systematic review of the literature for outcomes and complications using the Pipeline Embolization Device in unruptured cavernous carotid aneurysms. MATERIALS AND
methodsA retrospective search for cavernous carotid aneurysms from a prospectively collected data base of aneurysms treated with the Pipeline Embolization Device at our institution was performed. Baseline demographic, clinical, and laboratory values; intrainterventional data; and data at all follow-up visits were collected. A systematic review of the literature for complication data was performed with inquiries sent when clarification of data was needed.
resultsForty-three cavernous carotid aneurysms were included in the study. Our mean radiographic follow-up was 2.05 years. On last follow-up, 88.4% of the aneurysms treated had complete or near-complete occlusion. Aneurysm complete or near-complete occlusion rates at 6 months, 12 months, and 36 months were 81.4%, 89.7%, and 100%, respectively. Of patients with neuro-ophthalmologic deficits on presentation, 84.2% had improvement in their visual symptoms. Overall, we had a 0% mortality rate and a 2.3% major neurologic complication rate. Our systematic review of the literature yielded 227 cavernous carotid aneurysms treated with the Pipeline Embolization Device with mortality and morbidity rates of 0.4% and 3.1%, respectively.
conclusionsEndoluminal reconstruction with flow diversion for large unruptured cavernous carotid aneurysms can yield high efficacy with low complications. Further long-term data will be helpful in assessing the durability of the cure; however, we advocate a revisiting of current management paradigms for cavernous carotid aneurysms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.