ReviewCold Spring Harbor perspectives in medicine2014
Manipulation of the mononuclear phagocyte system by Mycobacterium tuberculosis.
Review in Cold Spring Harbor perspectives in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Glycolysis inhibition in tuberculosis-driven metabolic rewiring reduces HIV-1 spread in macrophages.Life science alliance · 2026Article
- Cytotoxic granules and effector molecules from immune cells in tuberculosis: Mechanisms of host defense and therapeutic potential.Virulence · 2025Review
- Deciphering macrophage dynamics and immune evasion strategies by the intracellular bacteria.Immunologic research · 2025Review
- Macrophage: A Cell With Many Faces and Functions in Tuberculosis.Frontiers in immunology · 2022Review
- Immunotherapy With 5, 15-DPP Mediates Macrophage M1 Polarization and Modulates SubsequentFrontiers in immunology · 2021Article
- Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation.PLoS pathogens · 2020Article
- Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells.Memorias do Instituto Oswaldo Cruz · 2019Article
- Platelets Regulate Pulmonary Inflammation and Tissue Destruction in Tuberculosis.American journal of respiratory and critical care medicine · 2018Article
- The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response toFrontiers in immunology · 2018Article
- Host-directed therapies for bacterial and viral infections.Nature reviews. Drug discovery · 2018Review
- Reinforcing the Functionality of Mononuclear Phagocyte System to Control Tuberculosis.Frontiers in immunology · 2018Review
- ESX secretion systems: mycobacterial evolution to counter host immunity.Nature reviews. Microbiology · 2016Review
- Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases.Pathogens and disease · 2016Review
- Article
- Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16(+) monocyte population via the IL-10/STAT3 axis.Cell research · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past 20 years, there has been an emerging appreciation about the role of the mononuclear phagocyte system (MPS) to control and eradicate pathogens. Likewise, there have been significant advances in dissecting the mechanisms involved in the microbial subversion of MPS cells, mainly affecting their differentiation and effector functions. Mycobacterium tuberculosis is a chronic bacterial pathogen that represents an enigma to the field because of its remarkable ability to thrive in humans. One reason is that M. tuberculosis renders a defective MPS compartment, which is perhaps the most ingenious strategy for survival in the host given the prominence of these cells to modulate microenvironments, their function as sentinels and orchestrators of the immune response, and their pathogenic role as reservoirs for microbial persistence. In this article, the principal strategies used by M. tuberculosis to subvert the MPS compartment are presented along with emerging concepts.
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