ReviewJournal of feline medicine and surgery2014
Pharmacological appetite stimulation: rational choices in the inappetent cat.
Review in Journal of feline medicine and surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 46 citations in OpenAlex.
- Mirtazapine revisited: new therapeutic perspectives and formulation advances.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Owner's Perspective About the Use of Mirtazapine Transdermal Ointment in Cats-A Survey-Based Study.Animals : an open access journal from MDPI · 2025Article
- Evaluation of the Short-Term Effects of Mirtazapine on Appetite Stimulants in Dogs: A Retrospective Study and a Placebo-Controlled Trial.Animals : an open access journal from MDPI · 2025Article
- Tools for the Approach of Fear, Anxiety, and Stress in the Domestic Feline: An Update.Veterinary medicine international · 2025Review
- Use of Gabapentin or Alprazolam in Cats during Postoperative, Short-Term Hospitalization.Animals : an open access journal from MDPI · 2024Article
- Feline Aortic Thromboembolism: Recent advances and future prospects.Journal of feline medicine and surgery · 2024Review
- Insights on discovery, efficacy, safety and clinical applications of ghrelin receptor agonist capromorelin in veterinary medicine.Veterinary research communications · 2024Review
- Use of feeding tubes in 112 cats in an internal medicine referral service (2015-2020).Journal of feline medicine and surgery · 2022Article
- 2022 ISFM Consensus Guidelines on Management of the Inappetent Hospitalised Cat.Journal of feline medicine and surgery · 2022Article
- Retrospective evaluation of maropitant and perioperative factors affecting postoperative appetite in cats.The Canadian veterinary journal = La revue veterinaire canadienne · 2021Article
- Amino Acids in the Nutrition, Metabolism, and Health of Domestic Cats.Advances in experimental medicine and biology · 2021Review
- Appetite-stimulating effect of gabapentin vs mirtazapine in healthy cats post-ovariectomy.Journal of feline medicine and surgery · 2020Article
- A double-blind, placebo-controlled, randomized study to evaluate the weight gain drug, mirtazapine transdermal ointment, in cats with unintended weight loss.Journal of veterinary pharmacology and therapeutics · 2019Article
- Tools for Managing Feline Problem Behaviours Psychoactive medications.Journal of feline medicine and surgery · 2018Article
- In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease.Journal of veterinary internal medicine · 2018Article
- Hepatic lipidosis: Clinical review drawn from collective effort.Journal of feline medicine and surgery · 2018Review
- Capromorelin: a ghrelin receptor agonist and novel therapy for stimulation of appetite in dogs.Veterinary medicine and science · 2018Review
- Mirtazapine toxicity in cats: retrospective study of 84 cases (2006-2011).Journal of feline medicine and surgery · 2016Article
- Update in feline therapeutics: clinical use of 10 emerging therapies.Journal of feline medicine and surgery · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
practical relevanceInappetence is a commonly encountered problem in feline medicine. Primary goals in managing the inappetent or anorectic cat are to diagnose and treat the underlying disease and reinstate adequate nutrition. RATIONALE: As cats are intolerant of prolonged periods of inadequate nutritional intake, especially given their propensity to develop hepatic lipidosis, their increased requirements for amino acids, and inability to slow their rate of gluconeogenesis, symptomatic therapy and nutritional support is often required during diagnostic investigations. CLINICAL CHALLENGES: Most cats presenting with reduced food intake will be suffering from an underlying systemic disease, and so the mechanism of action, pharmacokinetics and contraindications of appetite-stimulating medications will need to be considered in each case to ensure rational use of these agents. Pharmacological appetite stimulation should never replace monitoring and ensuring adequate caloric intake, and may not be appropriate in some cases, such as critically ill or severely malnourished patients. EVIDENCE BASE: While there are no medications approved specifically for the treatment of anorexia in cats, some drugs have proven efficacious in the clinical field. Although several agents have been used historically for appetite stimulation, due to potential side effects and/or lack of efficacy or predictability only cyproheptadine and mirtazapine can currently be recommended for use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.