Evidence map›Paper›PMID 25146182›Full record

ArticleJournal of dental research2014

Projections of U.S. Edentulism prevalence following 5 decades of decline.

G D Slade, A A Akinkugbe, A E Sanders

4 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 88 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 5 pooled it
18.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02686632 nacompletednot on this mapstarted 2016, after this paper: background citation

Improving Practice Guidelines for the Treatment of Denture-related Erythematous Stomatitis: A Pragmatic International Multicenter Randomized Controlled Trial

TypeinterventionalSponsorUniversité de MontréalRan2016 to 2018Enrolled52ConditionsDenture StomatitisArmsPalatal brushing
NCT02931968 completednot on this mapstarted 2017, after this paper: background citation

A Retrospective Clinical Study Evaluating Full-Arch Monolithic Zirconia Implant Supported Fixed Dental Prosthesis

TypeobservationalSponsorUniversity of North Carolina, Chapel HillRan2017 to 2018Enrolled22ConditionsEdentulousArmsMonolithic zirconia prosthesis
NCT03911336 phase4withdrawnnot on this mapstarted 2023, after this paper: background citation

Harnessing Chronomodulation to Enhance Osteogenesis - A Pilot Randomized Controlled Trial -

TypeinterventionalSponsorUniversity of IowaRan2023 to 2023Enrolled0ConditionsTooth LossArmsGroup A - test:Tooth extraction and intake of NSAID and a non-NSAID, Group B - Control 1: tooth extraction and intake of NSAID and a non-NSAID, Group C - Control 2: tooth extraction and intake of a Non-Nsaid
NCT05692609 unknown statusnot on this mapstarted 2023, after this paper: background citation

Comparison of the Acoustic Voice Quality of Edentulous Patients Treated With Two-implant Overdentures or All-on-4 Concept

TypeobservationalSponsorMarmara UniversityRan2023 to 2024Enrolled30ConditionsEdentulous Jaw
3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 5 syntheses or guidelines pooled it, 302 citations in OpenAlex.

  1. Pooled it
  2. Minimally Invasive Sinus Augmentation: A Systematic Review.Clinical implant dentistry and related research · 2025
    Pooled it
  3. Pooled it
  4. Tests to detect and inform the diagnosis of root caries.The Cochrane database of systematic reviews · 2020
    Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Article
  9. Do Temporal Changes in Complete Tooth Loss Point to Cohort Effects?Community dentistry and oral epidemiology · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Tooth Loss and 12-Year Mortality Risk in 8494 Older Adults From Ireland.Journal of the American Geriatrics Society · 2025
    Article
  18. Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

G D SladeDepartment of Dental Ecology, University of North Carolina at Chapel Hill, USA gary_slade@dentistry.unc.edu.
A A AkinkugbeDepartment of Dental Ecology, University of North Carolina at Chapel Hill, USA.
A E SandersDepartment of Dental Ecology, University of North Carolina at Chapel Hill, USA.
University of North Carolina at Chapel Hill · US

Funding

Training Program for the Next Generation of Oral Health Researchers (NextGen)T90DE021986 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI EVERETT, ERIC T. · 2011 to 2017
$2.3M
NIDCR NIH HHS 5T90DE021986-03NIDCR NIH HHS T90 DE021986
6 · The paper itself

Abstract

After decades of decline in prevalence of complete tooth loss (edentulism), the trend continues to be misinterpreted, producing flawed projections and misdirected health goals. We investigated population trends in edentulism among U.S. adults aged ≥ 15 yr by creating time-series data from 5 national cross-sectional health surveys: 1957-1958 (n ≈ 100,000 adults), 1971-1975 (n = 14,655 adults), 1988-1998 (n = 18,011 adults), 1999-2002 (n = 12,336 adults), and 2009-2012 (n = 10,522 adults). Birth cohort analysis was used to isolate age and cohort effects. Geographic and sociodemographic variation in prevalence was investigated with a sixth U.S. survey of 432,519 adults conducted in 2010. Prevalence through 2050 was projected with age-cohort regression models using Monte-Carlo simulation of prediction intervals. Across the 5-decade observation period, edentulism prevalence declined from 18.9% in 1957-1958 (95% confidence limits: 18.4%, 19.4%) to 4.9% in 2009-2012 (95% confidence limits: 4.0%, 5.8%). The most influential determinant of the decline was the passing of generations born before the 1940s, whose rate of edentulism incidence (5%-6% per decade of age) far exceeded later cohorts (1%-3% per decade of age). High-income households experienced a greater relative decline, although a smaller absolute decline, than low-income households. By 2010, edentulism was a rare condition in high-income households, and it had contracted geographically to states with disproportionately high poverty. With the passing of generations born in the mid-20th century, the rate of decline in edentulism is projected to slow, reaching 2.6% (95% prediction limits: 2.1%, 3.1%) by 2050. The continuing decline will be offset only partially by population growth and population aging such that the predicted number of edentulous people in 2050 (8.6 million; 95% prediction limits: 6.8 million, 10.3 million) will be 30% lower than the 12.2 million edentulous people in 2010.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsAsianBehavioral Risk Factor Surveillance SystemBlack or African AmericanCohort StudiesCross-Sectional StudiesFemaleGeographyHispanic or LatinoHumansIncidenceIncomecross-sectional studiesdental health surveysedentulousNational Health and Nutrition Examination Surveysocioeconomic factorstime factors

Identifiers

PMID25146182
PMCPMC4212322
OpenAlexW2140696174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.