Evidence map›Paper›PMID 25145817›Full record

SynthesisWorld journal of surgery2014

Primary fascial closure with laparoscopic ventral hernia repair: systematic review.

Duyen H Nguyen, Mylan T Nguyen, Erik P Askenasy, Lillian S Kao, Mike K Liang

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04143776 (Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction), which is not on this map. Cited by 66 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04143776 withdrawnnot on this mapstarted 2020, after this paper: background citation

Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction: The REPARE-study

TypeobservationalSponsorBispebjerg HospitalRan2020 to 2020Enrolled0ConditionsHernia, Ventral, Hernia Incisional, Acute Kidney Injury, Restrictive Lung DiseaseArmsAbdominal reconstruction
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Early outcomes of umbilical hernia repair with mesh suture.Hernia : the journal of hernias and abdominal wall surgery · 2026
    Article
  14. Article
  15. Robotic sugarbaker parastomal hernia repair: updated series and outcomes.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  16. Article
  17. Article
  18. Modified Chevrel Technique: A Lifesaver for Surgeons.Medicina (Kaunas, Lithuania) · 2024
    Article
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Duyen H NguyenDepartment of Surgery, University of Texas Health Science Center, 5656 Kelley Street, Houston, TX, 77026, USA.
Mylan T Nguyen
Erik P Askenasy
Lillian S Kao
Mike K Liang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laparoscopic ventral hernia repair (LVHR) has grown in popularity. Typically, this procedure is performed with a mesh bridge technique that results in high rates of seroma, eventration (bulging), and patient dissatisfaction. In an effort to avoid these complications, there is growing interest in the role of laparoscopic primary fascial closure with intraperitoneal mesh placement. This systematic review evaluated the outcomes of closure of the central defect during LVHR. A literature search of PubMed, Cochrane databases, and Embase was conducted using PRISMA guidelines. MINORS was used to assess the methodologic quality. Primary outcome was hernia recurrence. Secondary outcomes were surgical-site infection, seroma formation, bulging, and patient-centered items (satisfaction, chronic pain, functional status). Eleven studies were identified, eight of which were case series (level 4 data). Three comparative studies examined the difference between closure and nonclosure of the fascial defect during laparoscopic ventral incisional hernia repairs (level 3 and 4 data). These studies suggested that primary fascial closure (n = 138) compared to nonclosure (n = 255) resulted in lower recurrence rates (0-5.7 vs. 4.8-16.7 %) and seroma formation rates (5.6-11.4 vs. 4.3-27.8 %). Follow-up periods for both groups were similar (1-108 months). Only one study evaluated patient function and clinical bulging. It showed better outcomes with primary fascial closure. Closure of the central defect during LVHR resulted in less recurrence, bulging, and seroma than nonclosure. Patients with closure were more satisfied with the results and had better functional status. The quality of the data was poor, however. A randomized controlled trial to evaluate the role of closure of the central defect during LVHR is warranted.

Indexed as

FasciotomyWound Closure TechniquesAdultChronic PainFemaleHernia, VentralHerniorrhaphyHumansLaparoscopyMaleMiddle AgedPatient SatisfactionRecurrenceSeromaSurgical Wound Infection

Identifiers

PMID25145817

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.