ReviewAmerican journal of preventive medicine2014
Neurobiological risk factors for suicide: insights from brain imaging.
Review in American journal of preventive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- The association between white matter hyperintensities and suicide attempts in affective disorders: a systematic review and meta-analysis.Translational psychiatry · 2025Pooled it
- Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group.Translational psychiatry · 2017Pooled it
- Anhedonia as a clinical correlate of suicidal thoughts in clinical ketamine trials.Journal of affective disorders · 2017Trial
- Factors influencing suicidal ideation in Chinese adolescents with first-episode depressive disorder: a cross-sectional study.BMC psychology · 2026Article
- Exploring Brain Network Dynamics in Suicide Attempt Survivors Using EEG Microstate Analysis.Brain topography · 2025Article
- Disrupted small-world white matter networks in patients with major depression and recent suicide plans or attempts.Brain imaging and behavior · 2024Article
- Ventromedial prefrontal cortex activation and neurofeedback modulation during episodic future thinking for individuals with suicidal thoughts and behaviors.Behaviour research and therapy · 2024Article
- Event-Related Potential Markers of Suicidality in Adolescents.The international journal of neuropsychopharmacology · 2023Article
- Aberrant connectivity in the right amygdala and right middle temporal gyrus before and after a suicide attempt: Examining markers of suicide risk.Journal of affective disorders · 2023Article
- A resting state EEG study on depressed persons with suicidal ideation.IBRO neuroscience reports · 2023Article
- DNA Methylation of Genes Involved in the HPA Axis in Presence of Suicide Behavior: A Systematic Review.Brain sciences · 2023Review
- Machine learning based identification of structural brain alterations underlying suicide risk in adolescents.Discover mental health · 2023Article
- Diffusion tensor imaging studies on subjects with suicidal thoughts and behaviors: A descriptive literature review.Brain and behavior · 2022Review
- Smaller caudate gray matter volume is associated with greater implicit suicidal ideation in depressed adolescents.Journal of affective disorders · 2021Article
- Suicide Contagion.Current trauma reports · 2021Review
- An Exploratory Cohort Study of the Association between the Level of Testosterone and Suicidal Ideation in Hospitalized Adolescent Females with Depression in China.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Using resting-state intrinsic network connectivity to identify suicide risk in mood disorders.Psychological medicine · 2020Article
- ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing.Translational psychiatry · 2020Review
- Understanding the Complex of Suicide in Depression: from Research to Clinics.Psychiatry investigation · 2020Article
- Caudothalamic dysfunction in drug-free suicidally depressed patients: an MEG study.European archives of psychiatry and clinical neuroscience · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
contextThis article reviews neuroimaging studies on neural circuitry associated with suicide-related thoughts and behaviors to identify areas of convergence in findings. Gaps in the literature for which additional research is needed are identified. EVIDENCE ACQUISITION: A PubMed search was conducted and articles published before March 2014 were reviewed that compared individuals who made suicide attempts to those with similar diagnoses who had not made attempts or to healthy comparison subjects. Articles on adults with suicidal ideation and adolescents who had made attempts, or with suicidal ideation, were also included. Reviewed imaging modalities included structural magnetic resonance imaging, diffusion tensor imaging, single photon emission computed tomography, positron emission tomography, and functional magnetic resonance imaging. EVIDENCE SYNTHESIS: Although many studies include small samples, and subject characteristics and imaging methods vary across studies, there were convergent findings involving the structure and function of frontal neural systems and the serotonergic system.
conclusionsThese initial neuroimaging studies of suicide behavior have provided promising results. Future neuroimaging efforts could be strengthened by more strategic use of common data elements and a focus on suicide risk trajectories. At-risk subgroups defined by biopsychosocial risk factors and multidimensional assessment of suicidal thoughts and behaviors may provide a clearer picture of the neural circuitry associated with risk status-both current and lifetime. Also needed are studies investigating neural changes associated with interventions that are effective in risk reduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.