ArticlePloS one2014
Closely related NDM-1-encoding plasmids from Escherichia coli and Klebsiella pneumoniae in Taiwan.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 40 citations in OpenAlex.
- Tracking the Emergence and Dissemination of aMicrobiology spectrum · 2023Article
- Diversity of Bacterial Clones and Plasmids of NDM-1 ProducingMicroorganisms · 2023Article
- Back to the Origin:Microbiology spectrum · 2022Article
- Genetic basis of molecular mechanisms in β-lactam resistant gram-negative bacteria.Microbial pathogenesis · 2021Review
- Article
- Trade-Offs between Antibacterial Resistance and Fitness Cost in the Production of Metallo-β-Lactamases by Enteric Bacteria Manifest as Sporadic Emergence of Carbapenem Resistance in a Clinical Setting.Antimicrobial agents and chemotherapy · 2021Article
- Genomic analysis revealing the resistance mechanisms of extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolated from pig and humans in Malaysia.International microbiology : the official journal of the Spanish Society for Microbiology · 2021Article
- Nosocomial Outbreak of Carbapenemase-ProducingFrontiers in microbiology · 2021Article
- A prolonged multispecies outbreak of IMP-6 carbapenemase-producing Enterobacterales due to horizontal transmission of the IncN plasmid.Scientific reports · 2020Article
- Emergence of NDM-5-ProducingFrontiers in microbiology · 2020Article
- Complete-Genome Sequencing and Comparative Genomic Characterization of an IMP-4 ProducingInfection and drug resistance · 2020Article
- Resistance ofFrontiers in microbiology · 2020Article
- Complex Class 1 Integron in a ClinicalFrontiers in microbiology · 2019Article
- The successful containment of a hospital outbreak caused by NDM-1-producing Klebsiella pneumoniae ST307 using active surveillance.PloS one · 2019Article
- Simultaneous three Enterobacteriaceae with differentInfection and drug resistance · 2018Article
- Draft Genome Sequence of theGenome announcements · 2017Article
- New Delhi metallo-β-lactamase-1 (NDM-1)IDCases · 2017Article
- Dissemination of IMP-4-encoding pIMP-HZ1-related plasmids among Klebsiella pneumoniae and Pseudomonas aeruginosa in a Chinese teaching hospital.Scientific reports · 2016Article
- Genomic Characteristics of NDM-Producing Enterobacteriaceae Isolates in Australia and Their blaNDM Genetic Contexts.Antimicrobial agents and chemotherapy · 2016Article
- Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods.Frontiers in microbiology · 2016Review
Corrections and comments
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Authors and funding
8 authors at 7 institutions in 1 country.
Funding
Abstract
objectiveTwo plasmids carrying blaNDM-1 isolated from carbapenem-resistant Klebsiella pneumoniae (CR-KP) and carbapenem-resistant Escherichia coli (CR-EC) were sequenced. CR-KP and CR-EC were isolated from two Taiwanese patients without travel histories.
methodsComplete sequencing of the plasmids (pLK75 and pLK78) was conducted using a shotgun approach. Annotation of the contigs was performed using the RAST Server, followed by manual inspection and correction.
resultsThese similar plasmids were obtained from two patients with overlapping stays at the same hospital. The pLK75 and pLK78 plasmids were 56,489-bp and 56,072-bp in length, respectively. Plasmid annotation revealed a common backbone similar to the IncN plasmid pR46. The regions flanking the blaNDM-1 genes in these plasmids were very similar to plasmid pNDM-HU01 in Japan, which contains a complex class 1 integron located next to an ISCR1 element. The ISCR1 element has been suggested to provide a powerful mechanism for mobilising antibiotic resistance genes.
conclusionTwo indigenous NDM-1-producing Enterobacteriaceae cases were identified for the first time in Taiwan, highlighting the alarming introduction of NDM-1-producing Enterobacteriaceae in this region.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.