ArticlePLoS pathogens2014
Characterization of an insecticidal toxin and pathogenicity of Pseudomonas taiwanensis against insects.
Article in PLoS pathogens, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Assessment of Rhodococcus sp. (MG1) induced biochemical alterations and genotoxicity in Spodoptera litura.Scientific reports · 2026Article
- Biotransformation of As, Cr, Hg, and Mn by Pseudomonadota: chances and risks.Biodegradation · 2025Review
- Evaluation of Bacterial Communities ofInsects · 2025Article
- Isolation, identification and pathogenicity of local entomopathogenic bacteria as biological control agents against the wild cochineal Dactylopius opuntiae (Cockerell) on cactus pear in Morocco.Scientific reports · 2023Article
- Synergistic and additive interactions of Shewanella sp., Pseudomonas sp. and Thauera sp. with chlorantraniliprole and emamectin benzoate for controlling Spodoptera litura (Fabricius).Scientific reports · 2023Article
- Larvicidal, growth inhibitory and biochemical effects of soil bacterium, Pseudomonas sp. EN4 against Spodoptera litura (Fab.) (Lepidoptera: Noctuidae).BMC microbiology · 2023Article
- Genetic Engineering ofAccess microbiology · 2023Article
- Associated bacterial communities, confrontation studies, and comparative genomics reveal important interactions betweenFrontiers in fungal biology · 2023Article
- Insecticidal and growth inhibitory activity of gut microbes isolated from adults of Spodoptera litura (Fab.).BMC microbiology · 2022Article
- Stable-Isotope-Informed, Genome-Resolved Metagenomics Uncovers Potential Cross-Kingdom Interactions in Rhizosphere Soil.mSphere · 2021Article
- Genome-wide dissection reveals diverse pathogenic roles of bacterial Tc toxins.PLoS pathogens · 2021Article
- Different Cultivation Environments Affect the Yield, Bacterial Community and Metabolites ofFrontiers in microbiology · 2021Article
- Whole Genome Sequencing and TnInternational journal of molecular sciences · 2020Article
- Infection ofFrontiers in microbiology · 2020Article
- Article
- Genetic variation associated with infection and the environment in the accidental pathogenCommunications biology · 2019Article
- Coping with Environmental Eukaryotes; Identification ofMicroorganisms · 2018Article
- A selective insecticidal protein from Pseudomonas mosselii for corn rootworm control.Plant biotechnology journal · 2018Article
- Article
- Bacterial Community Structure in the Asian Rice Gall Midge Reveals a Varied Microbiome Rich in Proteobacteria.Scientific reports · 2017Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Pseudomonas taiwanensis is a broad-host-range entomopathogenic bacterium that exhibits insecticidal activity toward agricultural pests Plutella xylostella, Spodoptera exigua, Spodoptera litura, Trichoplusia ni and Drosophila melanogaster. Oral infection with different concentrations (OD = 0.5 to 2) of wild-type P. taiwanensis resulted in insect mortality rates that were not significantly different (92.7%, 96.4% and 94.5%). The TccC protein, a component of the toxin complex (Tc), plays an essential role in the insecticidal activity of P. taiwanensis. The ΔtccC mutant strain of P. taiwanensis, which has a knockout mutation in the tccC gene, only induced 42.2% mortality in P. xylostella, even at a high bacterial dose (OD = 2.0). TccC protein was cleaved into two fragments, an N-terminal fragment containing an Rhs-like domain and a C-terminal fragment containing a Glt symporter domain and a TraT domain, which might contribute to antioxidative stress activity and defense against macrophagosis, respectively. Interestingly, the primary structure of the C-terminal region of TccC in P. taiwanensis is unique among pathogens. Membrane localization of the C-terminal fragment of TccC was proven by flow cytometry. Sonicated pellets of P. taiwanensis ΔtccC strain had lower toxicity against the Sf9 insect cell line and P. xylostella larvae than the wild type. We also found that infection of Sf9 and LD652Y-5d cell lines with P. taiwanensis induced apoptotic cell death. Further, natural oral infection by P. taiwanensis triggered expression of host programmed cell death-related genes JNK-2 and caspase-3.
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