Evidence map›Paper›PMID 25144324›Full record

ArticleMedicine2014

Obstructive sleep apnea and cardiovascular comorbidities: a large epidemiologic study.

Hanna Gilat, Shlomo Vinker, Inon Buda, Ethan Soudry, Michal Shani, Gideon Bachar

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05311280 (The Effect of High Intensity Interval Exercise and Myofunctional Therapy on Obstructive Sleep Apnea), which is not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05311280 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of High Intensity Interval Exercise and Myofunctional Therapy on Obstructive Sleep Apnea: a Randomized Clinical Controlled Trial

TypeinterventionalSponsorTaoyuan General HospitalRan2022 to 2022Enrolled40ConditionsObstructive Sleep ApneaArmshigh intensity interval training plus myotherapy, home exercise plus myotherapy
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
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  7. Sleep and periodontal health.Periodontology 2000 · 2024
    Review
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  16. Assessment of the cognitive function in adult Egyptian patients with obstructive sleep apnea using the Montreal Cognitive Assessment: a retrospective large-scale study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Hanna GilatDepartment of Otolaryngology-Head and Neck Surgery, Rabin Medical Center, Petach Tikva (HG, IB, ES, GB); Sackler Faculty of Medicine (HG, IB, GB); Department of Family Medicine, Sackler School of Medicine (SV, MS), Tel Aviv University; Chief Physician Office, Clalit Health Services (SV), Tel Aviv; and Department of Family Medicine, Central District, Clalit Health Services, Rishon Le-Zion (MS), Israel.
Shlomo Vinker
Inon Buda
Ethan Soudry
Michal Shani
Gideon Bachar
Bridge University · SSTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is a common disorder, characterized by cyclic cessation of airflow for 10 seconds or more. There is growing awareness that OSA is related to the development and progression of cardiovascular disease. However, only a few studies have associated OSA directly to major cardiovascular events. The aim of this study was to evaluate the relationship between OSA and cardiovascular morbidity in a well defined population of patients.The electronic database of the central district of a major health management organization was searched for all patients diagnosed with OSA in 2002-2010. For each patient identified, an age- and sex-matched patient was randomly selected from the members of the same health management organization who did not have OSA. Data on demographics, socioeconomic status, and relevant medical parameters were collected as well.The study population included 2797 patients, average age 58.1, in which 76.6% were males. There was a significant correlation between OSA and the presence of ischemic heart disease (P < 0.001), pulmonary hypertension (P < 0.001), congestive heart failure (P < 0.001), cardiomyopathy (P = 0.003), and arrhythmia (P < 0.001). OSA was also significantly correlated with low socioeconomic status (P < 0.001).OSA and cardiovascular disease were strongly correlated. As such, early diagnosis and treatment of OSA may change the course of both diseases. We suggest that sleep disordered breathing should be routinely assessed in patients with cardiovascular problems. An ear-nose-throat evaluation may also be important to rule out anatomic disorders that cause upper airway obstruction.

Indexed as

Cardiovascular DiseasesComorbidityEpidemiologic StudiesFemaleHumansIsraelMaleMiddle AgedPrevalenceRisk FactorsSleep Apnea, Obstructive

Identifiers

PMID25144324
PMCPMC4602425
OpenAlexW1968705065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.