Observational studyJournal of hypertension2014
Predicting out-of-office blood pressure level using repeated measurements in the clinic: an observational cohort study.
Observational study in Journal of hypertension, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03858595 (Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy by Regular Monitoring of Weight Gain and Blood Pressure), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy by Regular Monitoring of Weight Gain and Blood Pressure: A Pilot Randomized Controlled Trial
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Guideline
- Clinical Impact of 3- Vs. 5-Minute Delay and 30- Vs. 60-Second Intervals on Unattended Automated Office Blood Pressure Measurements.American journal of hypertension · 2025Article
- Cutoffs for white-coat and masked blood pressure effects: an ambulatory blood pressure monitoring study.Journal of human hypertension · 2024Article
- Review
- Comparative accuracies of automated and manual office blood pressure measurements in a Chinese population.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Blood pressure cutoffs for white-coat and masked effects in a large population undergoing home blood pressure monitoring.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Hypertension: history and development of established and novel treatments.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Review
- Prospective external validation of the Predicting Out-of-OFfice Blood Pressure (PROOF-BP) strategy for triaging ambulatory monitoring in the diagnosis and management of hypertension: observational cohort study.BMJ (Clinical research ed.) · 2018Observational
- Blood pressure measurement: a call to arms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016Article
- Observational
- Uncontrolled hypertension in older patients: markers and associated factors to masked and white-coat effect.Journal of geriatric cardiology : JGC · 2016Article
- In-Clinic Blood Pressure Prediction of Normal Ambulatory Blood Pressure Monitoring in Pediatric Hypertension Referrals.Congenital heart disease · 2016Article
- Predicting Out-of-Office Blood Pressure in the Clinic (PROOF-BP): Derivation and Validation of a Tool to Improve the Accuracy of Blood Pressure Measurement in Clinical Practice.Hypertension (Dallas, Tex. : 1979) · 2016Article
- [Management of arterial hypertension].Herz · 2015Article
- Learning lessons from operational research in infectious diseases: can the same model be used for noncommunicable diseases in developing countries?Advances in medical education and practice · 2014Review
- Gene silencing in DNA damage repair.Cellular and molecular life sciences : CMLS · 2004Review
Corrections and comments
- Commented on by
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesIdentification of people with lower (white-coat effect) or higher (masked effect) blood pressure at home compared to the clinic usually requires ambulatory or home monitoring. This study assessed whether changes in SBP with repeated measurement at a single clinic predict subsequent differences between clinic and home measurements.
methodsThis study used an observational cohort design and included 220 individuals aged 35-84 years, receiving treatment for hypertension, but whose SBP was not controlled. The characteristics of change in SBP over six clinic readings were defined as the SBP drop, the slope and the quadratic coefficient using polynomial regression modelling. The predictive abilities of these characteristics for lower or higher home SBP readings were investigated with logistic regression and repeated operating characteristic analysis.
resultsThe single clinic SBP drop was predictive of the white-coat effect with a sensitivity of 90%, specificity of 50%, positive predictive value of 56% and negative predictive value of 88%. Predictive values for the masked effect and those of the slope and quadratic coefficient were slightly lower, but when the slope and quadratic variables were combined, the sensitivity, specificity, positive and negative predictive values for the masked effect were improved to 91, 48, 24 and 97%, respectively.
conclusionCharacteristics obtainable from multiple SBP measurements in a single clinic in patients with treated hypertension appear to reasonably predict those unlikely to have a large white-coat or masked effect, potentially allowing better targeting of out-of-office monitoring in routine clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.