ArticleJournal of perinatology : official journal of the California Perinatal Association2015
The Neonatal Pain, Agitation and Sedation Scale and the bedside nurse's assessment of neonates.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- The analgesic effects of human milk odor in preterm neonates: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2026Pooled it
- Clinical rating scales for assessing pain in newborn infants.The Cochrane database of systematic reviews · 2025Pooled it
- Neonatal Pain, Agitation, and Sedation Scale's use, reliability, and validity: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2020Pooled it
- Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) - short version.German medical science : GMS e-journal · 2015Guideline
- EDIN and N-PASS pain scale comparison in asphyxiated newborns treated with therapeutic hypothermia.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Rapid, Safe, and Tolerable Healing of Pediatric Skin Injuries with Blue Light Therapy: An Observational Case Series.Children (Basel, Switzerland) · 2025Article
- Automated Deep Learning Approach for Post-Operative Neonatal Pain Detection and Prediction through Physiological Signals.Proceedings. IEEE International Symposium on Computer-Based Medical Systems · 2025Article
- Neonatal delirium: fact or fiction? A study protocol of a prospective, observational study at the Neonatal Intensive Care Unit (NICU).BMJ paediatrics open · 2025Article
- Case Report: Holistic approach to management of an infant with severe osteogenesis imperfecta in the neonatal intensive care unit.Frontiers in pediatrics · 2025Article
- Neonatal intensive care nurses' assessment of preterm infants' pain and sedation: inter-rater reliability of the neonatal pain, agitation, and sedation scale.Frontiers in pediatrics · 2025Article
- Identification of a Conversion Factor for Dexmedetomidine to Clonidine Transitions.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Effectiveness and Safety of Dexmedetomidine in Neonates With Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Initial feasibility and challenges of hyperpolarizedMagnetic resonance in medicine · 2023Article
- Characteristics of Critically Ill Infants at the End of Life in the Neonatal Intensive Care Unit.Journal of palliative medicine · 2023Article
- Intercostal Nerve Cryoablation is Associated with Reduced Opioid Use in Pediatric Oncology Patients.The Journal of surgical research · 2023Article
- Use of glucose for pain management in premature neonates: a systematic review and meta-analysis protocol.BMJ open · 2021Article
- Article
- Electronic Health Record-Embedded Decision Support Platform for Morphine Precision Dosing in Neonates.Clinical pharmacology and therapeutics · 2020Article
- Opioid and benzodiazepine use during therapeutic hypothermia in encephalopathic neonates.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Collagenase for Wound Debridement in the Neonatal Intensive Care Unit: A Retrospective Case Series.Pediatric dermatology · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo determine the reliability of an objective measure of pain, agitation and sedation using the Neonatal Pain, Agitation and Sedation Scale (N-PASS) compared with nursing bedside assessment. STUDY
designNeonates admitted in neonatal intensive care unit over a 6-month period were eligible. Pain and sedation were assessed with N-PASS, and a subjective questionnaire was administered to the bedside nurse.
resultA total of 218 neonates were eligible (median: gestational age 34.6 weeks, age at assessment 7 days). N-PASS pain score correlated significantly with both nurses' pain score (Spearman coefficient (r)=0.37; P<0.001) and agitation score (r=0.56; P<0.001). N-PASS sedation score correlated with nurses' sedation score (r=-0.39; P<0.001). Adjusting for gestational age, day of life, intrauterine drug exposure and use of high frequency ventilation only slightly attenuated the correlations (r=0.36, 0.55 and -0.31, respectively).
conclusionThe N-PASS captures nursing assessment of pain, agitation and sedation in this broad population and provides a quantitative assessment of subjective descriptions that often drives patient therapy.
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