Evidence map›Paper›PMID 25143957›Full record

ReviewJournal of immunology research2014

HLA-G as a tolerogenic molecule in transplantation and pregnancy.

Vera Rebmann, Fabiola da Silva Nardi, Bettina Wagner, Peter A Horn

Abstract readReview
In one paragraph

Review in Journal of immunology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. HLA-G, IL-6 and TGF-β in Seminal Plasma as Potential Biomarkers of ART Outcome.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. The Immune ModulationInternational journal of molecular sciences · 2024
    Article
  11. Article
  12. International journal of molecular sciences · 2023
    Article
  13. Article
  14. Activation of immune signals during organ transplantation.Signal transduction and targeted therapy · 2023
    Review
  15. Article
  16. Article
  17. The association of decreased HLA-GMicrobial pathogenesis · 2022
    Article
  18. Role of HLA-G in Viral Infections.Frontiers in immunology · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vera RebmannInstitute for Transfusion Medicine, University Hospital Essen, Virchowstraße 179, 45147 Essen, Germany.ORCID 0000-0003-4660-3870
Fabiola da Silva NardiInstitute for Transfusion Medicine, University Hospital Essen, Virchowstraße 179, 45147 Essen, Germany ; CAPES Foundation, Ministry of Education of Brazil, 70.040-020 Brasília, DF, Brazil.
Bettina WagnerInstitute for Transfusion Medicine, University Hospital Essen, Virchowstraße 179, 45147 Essen, Germany.
Peter A HornInstitute for Transfusion Medicine, University Hospital Essen, Virchowstraße 179, 45147 Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HLA-G is a nonclassical HLA class I molecule. In allogeneic situations such as pregnancy or allograft transplantation, the expression of HLA-G has been related to a better acceptance of the fetus or the allograft. Thus, it seems that HLA-G is crucially involved in mechanisms shaping an allogeneic immune response into tolerance. In this contribution we focus on (i) how HLA-G is involved in transplantation and human reproduction, (ii) how HLA-G is regulated by genetic and microenvironmental factors, and (iii) how HLA-G can offer novel perspectives with respect to therapy.

Indexed as

Transplantation ImmunologyFemaleGene Expression RegulationHLA-G AntigensHumansImmune TolerancePregnancyProtein BindingReceptors, ImmunologicReproductionTransplantation, HomologousHLA-G AntigensReceptors, Immunologic

Identifiers

PMID25143957
PMCPMC4131093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.