ArticleInternational journal of nanomedicine2014
Biophysical evaluation of cells on nanotubular surfaces: the effects of atomic ordering and chemistry.
Article in International journal of nanomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed.
- The rational design, biofunctionalization and biological properties of orthopedic porous titanium implants: a review.Frontiers in bioengineering and biotechnology · 2025Review
- Evaluation of the Biocompatibility and Osteogenic Properties of Metal Oxide Coatings Applied by Magnetron Sputtering as Potential Biofunctional Surface Modifications for Orthopedic Implants.Materials (Basel, Switzerland) · 2022Article
- Bioactivity of an Experimental Dental Implant with Anodized Surface.Journal of functional biomaterials · 2021Article
- Local and Systemic In Vivo Responses to Osseointegrative Titanium Nanotube Surfaces.Nanomaterials (Basel, Switzerland) · 2021Article
- Characterization of Optimized TiOInternational journal of nanomedicine · 2021Article
- Nanoparticles and Nanostructured Surface Fabrication for Innovative Cranial and Maxillofacial Surgery.Materials (Basel, Switzerland) · 2020Review
- Titanium Dioxide Thin Films Obtained by Atomic Layer Deposition Promotes Osteoblasts' Viability and Differentiation Potential While Inhibiting Osteoclast Activity-Potential Application for Osteoporotic Bone Regeneration.Materials (Basel, Switzerland) · 2020Article
- Influence of Titanium Oxide Pillar Array Nanometric Structures and Ultraviolet Irradiation on the Properties of the Surface of Dental Implants-A Pilot Study.Nanomaterials (Basel, Switzerland) · 2019Article
- Article
- Synthesis, Characterization, and Photocatalytic Properties of Sulfur- and Carbon-Codoped TiO2 Nanoparticles.Nanoscale research letters · 2016Article
- Enhanced in vitro angiogenic behaviour of human umbilical vein endothelial cells on thermally oxidized TiO2 nanofibrous surfaces.Scientific reports · 2016Article
- The janus facet of nanomaterials.BioMed research international · 2015Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After the implantation of a biomaterial in the body, the first interaction occurs between the cells in contact with the biomaterial surface. Therefore, evaluating the cell-substrate interface is crucial for designing a successful implant. In this study, the interaction of MC3T3 osteoblasts was studied on commercially pure and alloy (Ti6Al4V) Ti surfaces treated with amorphous and crystalline titanium dioxide nanotubes. The results indicated that the presence of nanotubes increased the density of osteoblast cells in comparison to bare surfaces (no nanotubes). More importantly, our finding shows that the chemistry of the substrate affects the cell density rather than the morphology of the cells. A novel approach based on the focused ion beam technique was used to investigate the biophysical cell-substrate interaction. The analysis revealed that portions of the cells migrated inside the crystalline nanotubes. This observation was correlated with the super hydrophilic properties of the crystalline nanotubes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.