Evidence map›Paper›PMID 25143583›Full record

ArticleJournal of clinical microbiology2014

Characterization of multiple cytomegalovirus drug resistance mutations detected in a hematopoietic stem cell transplant recipient by recombinant phenotyping.

Emilien Drouot, Jocelyne Piret, Marc H Lebel, Guy Boivin

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Viruses · 2021
    Article
  7. Antiviral Drugs Against Herpesviruses.Advances in experimental medicine and biology · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Approach to drug-resistant cytomegalovirus in transplant recipients.Current opinion in infectious diseases · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emilien DrouotResearch Center in Infectious Diseases, CHU de Québec and Université Laval, Québec, QC, Canada.
Jocelyne PiretResearch Center in Infectious Diseases, CHU de Québec and Université Laval, Québec, QC, Canada.
Marc H LebelCHU Ste-Justine and Université de Montréal, Montréal, QC, Canada.
Guy BoivinResearch Center in Infectious Diseases, CHU de Québec and Université Laval, Québec, QC, Canada guy.boivin@crchudequebec.ulaval.ca.

Funding

Canadian Institutes of Health Research MOP-86583
6 · The paper itself

Abstract

Cytomegalovirus resistance to antivirals is a major problem in transplant recipients. We evaluated the impact of five mutations (A594V, L595F, and E655K in the UL97 gene and V526L and E756K in the UL54 gene), detected in a blood sample from a stem cell transplant recipient, on drug susceptibilities and replicative capacities of recombinant viruses.

Indexed as

Drug Resistance, ViralHematopoietic Stem Cell TransplantationMutation, MissenseAntiviral AgentsChild, PreschoolCytomegalovirusCytomegalovirus InfectionsFemaleHumansImmunocompromised HostVirus ReplicationAntiviral Agents

Identifiers

PMID25143583
PMCPMC4313248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.