Evidence map›Paper›PMID 25143338›Full record

ArticleClinical and vaccine immunology : CVI2014

Detection of antibodies to the biofilm exopolysaccharide of Histophilus somni following infection in cattle by enzyme-linked immunosorbent assay.

Yu Pan, Taylor Fisher, Christina Olk, Thomas J Inzana

Abstract readEvaluation Study
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Biofilm and wound healing: from bench to bedside.European journal of medical research · 2023
    Review
  2. Advances in the Sensing and Treatment of Wound Biofilms.Angewandte Chemie (International ed. in English) · 2022
    Review
  3. Advances in the Sensing and Treatment of Wound Biofilms.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022
    Review
  4. Review
  5. Polymicrobial Biofilm Interaction BetweenFrontiers in microbiology · 2020
    Article
  6. Article
  7. Review
  8. Histophilosis as a Natural Disease.Current topics in microbiology and immunology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu PanVirginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Department of Biomedical Sciences and Pathobiology, Blacksburg, Virginia, USA.
Taylor FisherVirginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Department of Biomedical Sciences and Pathobiology, Blacksburg, Virginia, USA.
Christina OlkVirginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Department of Biomedical Sciences and Pathobiology, Blacksburg, Virginia, USA.
Thomas J InzanaVirginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Department of Biomedical Sciences and Pathobiology, Blacksburg, Virginia, USA Virginia Tech Carilion School of Medicine, Department of Basic Sciences, Roanoke, Virginia, USA tinzana@vt.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An enzyme-linked immunosorbent assay (ELISA) was developed to detect bovine antibodies to Histophilus somni exopolysaccharide (EPS), which is created during biofilm formation. When an index value of 0.268 was used, the sensitivity of the assay for infected calves was 90.5% at 3 weeks postinfection, but the number of positive animals increased by week 4. The specificity of the assay for healthy calves was 92.5%. The EPS ELISA may aid in identifying calves with H. somni diseases.

Indexed as

AnimalsAntibodies, BacterialCattleCattle DiseasesEnzyme-Linked Immunosorbent AssayPasteurellaceaePasteurellaceae InfectionsPolysaccharides, BacterialSensitivity and SpecificitySerologic TestsVeterinary MedicineAntibodies, BacterialPolysaccharides, Bacterial

Identifiers

PMID25143338
PMCPMC4266353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.