ArticleProceedings. Biological sciences2014
Starvation reveals the cause of infection-induced castration and gigantism.
Article in Proceedings. Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 55 citations in OpenAlex.
- The timings of host diapause and epidemic progression mediate host genetic diversity and future epidemic size inProceedings. Biological sciences · 2023Article
- Out of the 'host' box: extreme off-host conditions alter the infectivity and virulence of a parasitic bacterium.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Infection burdens and virulence under heat stress: ecological and evolutionary considerations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Genotypic variation in an ecologically important parasite is associated with host species, lake and spore size.Parasitology · 2021Article
- The Role of Microbiome and Genotype inGenes · 2021Article
- Article
- Role of temperature and carbonate system variability on a host-parasite system: Implications for the gigantism hypothesis.International journal for parasitology. Parasites and wildlife · 2019Article
- Assessment of parasite virulence in a natural population of a planktonic crustacean.BMC ecology · 2019Article
- Resource-driven changes to host population stability alter the evolution of virulence and transmission.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Environmental variation causes different (co) evolutionary routes to the same adaptive destination across parasite populations.Evolution letters · 2017Article
- Ecology, Virulence, and Phylogeny of Blastulidium paedophthorum, a Widespread Brood Parasite of Daphnia spp.Applied and environmental microbiology · 2015Article
- Statistical Mechanics of Zooplankton.PloS one · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parasites often induce life-history changes in their hosts. In many cases, these infection-induced life-history changes are driven by changes in the pattern of energy allocation and utilization within the host. Because these processes will affect both host and parasite fitness, it can be challenging to determine who benefits from them. Determining the causes and consequences of infection-induced life-history changes requires the ability to experimentally manipulate life history and a framework for connecting life history to host and parasite fitness. Here, we combine a novel starvation manipulation with energy budget models to provide new insights into castration and gigantism in the Daphnia magna-Pasteuria ramosa host-parasite system. Our results show that starvation primarily affects investment in reproduction, and increasing starvation stress reduces gigantism and parasite fitness without affecting castration. These results are consistent with an energetic structure where the parasite uses growth energy as a resource. This finding gives us new understanding of the role of castration and gigantism in this system, and how life-history variation will affect infection outcome and epidemiological dynamics. The approach of combining targeted life-history manipulations with energy budget models can be adapted to understand life-history changes in other disease systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.