ArticleMedical science monitor : international medical journal of experimental and clinical research2014
Suicidal behavior in schizophrenia may be related to low lipid levels.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- How do lipids influence risk of violence, self-harm and suicidality in people with psychosis? A systematic review.The Australian and New Zealand journal of psychiatry · 2022Pooled it
- Worldwide prevalence of suicidal ideation and suicide plan among people with schizophrenia: a meta-analysis and systematic review of epidemiological surveys.Translational psychiatry · 2021Pooled it
- Cannabinoid Receptors, Mental Pain and Suicidal Behavior: a Systematic Review.Current psychiatry reports · 2018Pooled it
- Serum lipid levels and suicidality: a meta-analysis of 65 epidemiological studies.Journal of psychiatry & neuroscience : JPN · 2016Pooled it
- In-Depth characterization of the shared genetic architecture of suicide attempts with other major psychiatric disorders.Translational psychiatry · 2026Article
- Study on the correlation between serum total cholesterol levels and suicidal ideation in patients with first-episode drug-naïve schizophrenia: a cross-sectional study.Frontiers in psychiatry · 2025Article
- Can neurocognition, brain neurotrophic factor, triglyceride, and total cholesterol predict suicidal ideation in first-episode Han Chinese patients with schizophrenia?Brain and behavior · 2024Article
- Prevalence and clinical correlates of psychotic symptoms in first-episode untreated female chinese patients with major depressive disorder.BMC psychiatry · 2023Article
- Age-specific associations between serum cholesterol levels and suicidal behaviors in patients with depressive disorders: A naturalistic prospective observational cohort study.Frontiers in psychiatry · 2023Article
- Aggression in Women with Schizophrenia Is Associated with Lower HDL Cholesterol Levels.International journal of molecular sciences · 2022Article
- DeepBiomarker: Identifying Important Lab Tests from Electronic Medical Records for the Prediction of Suicide-Related Events among PTSD Patients.Journal of personalized medicine · 2022Article
- mRNA Expression of the CUB and Sushi Multiple Domains 1 (ACS omega · 2021Article
- Patterns of Comorbidity of Suicide Attempters: An Update.Current psychiatry reports · 2016Review
- Copeptin levels and blood lipid profile in borderline patients with or without self-mutilation.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2016Article
- The association between altered lipid profile and suicide attempt among Tunisian patients with schizophrenia.Annals of general psychiatry · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLifetime suicide mortality in people with schizophrenia is approximately 4-5%, which is higher than in the general population. In mood disorders, many studies and meta-analyses have shown a link between suicidal behavior and low lipid levels, especially that of cholesterol, and some studies have also suggested such a relationship in schizophrenia. Therefore, the aim of the present study was to investigate a possible correlation between suicidal behavior and lipid levels in schizophrenia patients recently admitted to a psychiatric hospital. MATERIAL/
methodsOur study included 148 (69 males, 79 females) schizophrenia patients with a mean age of 32±10 years, all recently admitted due to acute exacerbation of their mental illness. Psychometric and laboratory assessments were made within 24-72 hours after hospital admission. The main purpose of the interview was to assess occurrence of any suicidal thoughts, suicidal tendencies, and/or suicide attempts during the 3 months prior to admission. Serum total, LDL and HDL cholesterol, as well as triglycerides and total lipids were measured.
resultsA significant association was found between suicidal thoughts and attempts and low total cholesterol, LDL cholesterol, triglycerides, and total lipids, in both male and female patients. In male patients with suicidal tendencies, correlation with low LDL cholesterol and triglycerides did not reach statistical significance. No association with suicidality was found with HDL cholesterol in subjects studied.
conclusionsThe results obtained suggest that, similar to depressed patients, low total and LDL cholesterol, triglycerides, and total lipids can be state-dependent risk factors for suicidal behavior in Polish patients with schizophrenia.
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