ArticleeLife2014
Reconceiving the hippocampal map as a topological template.
Article in eLife, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed.
- Spaces and sequences in the hippocampus: a homological perspective.Journal of computational neuroscience · 2026Article
- Topological Neuroscience: Linking Circuits to Function.Annual review of neuroscience · 2025Review
- Agency Modulation of Hippocampal Activity During Spatial Navigation.Research square · 2025Article
- Computational role of structure in neural activity and connectivity.Trends in cognitive sciences · 2024Review
- Topological structure of population activity in mouse visual cortex encodes densely sampled stimulus rotations.iScience · 2024Article
- Neural Trajectories of Conceptually Related Events.bioRxiv : the preprint server for biology · 2024Article
- Hippocampal cognitive and relational map paradigms explored by multisensory encoding recording with wide-field calcium imaging.iScience · 2024Article
- Metric information in cognitive maps: Euclidean embedding of non-Euclidean environments.PLoS computational biology · 2023Article
- A manifold neural population code for space in hippocampal coactivity dynamics independent of place fields.Cell reports · 2023Article
- Article
- How our understanding of memory replay evolves.Journal of neurophysiology · 2023Review
- Review
- Grid cells, border cells, and discrete complex analysis.Frontiers in computational neuroscience · 2023Article
- Making Sense of the Multiplicity and Dynamics of Navigational Codes in the Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Review
- Unusual Mathematical Approaches Untangle Nervous Dynamics.Biomedicines · 2022Review
- Neural basis of topographical disorientation in the primate posterior cingulate gyrus based on a labeled graph.AIMS neuroscience · 2022Article
- Spatial representability of neuronal activity.Scientific reports · 2021Article
- The grid code for ordered experience.Nature reviews. Neuroscience · 2021Review
- Neural population geometry: An approach for understanding biological and artificial neural networks.Current opinion in neurobiology · 2021Review
- Hippocampal place cells encode global location but not connectivity in a complex space.Current biology : CB · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The role of the hippocampus in spatial cognition is incontrovertible yet controversial. Place cells, initially thought to be location-specifiers, turn out to respond promiscuously to a wide range of stimuli. Here we test the idea, which we have recently demonstrated in a computational model, that the hippocampal place cells may ultimately be interested in a space's topological qualities (its connectivity) more than its geometry (distances and angles); such higher-order functioning would be more consistent with other known hippocampal functions. We recorded place cell activity in rats exploring morphing linear tracks that allowed us to dissociate the geometry of the track from its topology. The resulting place fields preserved the relative sequence of places visited along the track but did not vary with the metrical features of the track or the direction of the rat's movement. These results suggest a reinterpretation of previous studies and new directions for future experiments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.