Evidence map›Paper›PMID 25141102›Full record

ReviewInternational journal of molecular sciences2014

Recent advances of stem cell therapy for retinitis pigmentosa.

Yuxi He, Yan Zhang, Xin Liu, Emma Ghazaryan, Ying Li, Jianan Xie, Guanfang Su

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Utilization of Stem Cells in Medicine: A Narrative Review.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Regenerative mechanisms of stem cells and their clinical applications for degenerative eye diseases.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuxi HeDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. heyuxihot@163.com.
Yan ZhangDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. zhangy66@jlu.edu.cn.
Xin LiuDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. emperorsoninlow@163.com.
Emma GhazaryanDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. emmaghazaryan@163.com.
Ying LiDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. lyvoilet@163.com.
Jianan XieDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. 13844108986@163.com.
Guanfang SuDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, China. sugf2012@163.com.
Second Affiliated Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is a group of inherited retinal disorders characterized by progressive loss of photoreceptors and eventually leads to retina degeneration and atrophy. Until now, the exact pathogenesis and etiology of this disease has not been clear, and many approaches for RP therapies have been carried out in animals and in clinical trials. In recent years, stem cell transplantation-based attempts made some progress, especially the transplantation of bone marrow-derived mesenchymal stem cells (BMSCs). This review will provide an overview of stem cell-based treatment of RP and its main problems, to provide evidence for the safety and feasibility for further clinical treatment.

Indexed as

Bone Marrow CellsHumansMesenchymal Stem CellsRetinitis PigmentosaStem Cell Transplantation

Identifiers

PMID25141102
PMCPMC4159862
OpenAlexW2156089667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.