ArticlePloS one2014
Asthma during pregnancy in a population-based study--pregnancy complications and adverse perinatal outcomes.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Obesity and asthma during pregnancy: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Parental asthma and risk of autism spectrum disorder in offspring: A population and family-based case-control study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019Trial
- Study protocol for a randomised controlled trial evaluating the efficacy of a telehealth program--management of asthma with supportive telehealth of respiratory function in pregnancy (MASTERY©).BMC pulmonary medicine · 2015Trial
- Inhaled Corticosteroids Continuation in the First Trimester and Pregnancy Outcomes in Women With Asthma.JAMA network open · 2026Article
- Maternal asthma activity and offspring asthma: a linked-data population study in Australia and Sweden.BMJ open respiratory research · 2026Article
- Maternal asthma and the role of stress, sensitization, and lung function on pregnancy outcomes: MAESTRO cohort study.The journal of allergy and clinical immunology. Global · 2026Article
- Maternal asthma and lung function, childhood asthma and growth: the MAESTRO-Child study.ERJ open research · 2025Article
- Infant respiratory outcomes following asthma management and exacerbations in pregnancy.ERJ open research · 2025Article
- Pregnancy does not affect progression of mild experimental asthma in sheep.The Journal of physiology · 2025Article
- Maternal asthma during pregnancy and the likelihood of neurodevelopmental disorders in offspring.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review).Experimental and therapeutic medicine · 2024Review
- Feasibility of remote spirometry monitoring of asthma in pregnancy.Respiratory medicine · 2024Article
- Autism likelihood in infants born to mothers with asthma is associated with blood inflammatory gene biomarkers in pregnancy.Brain, behavior, & immunity - health · 2024Article
- Assessing adverse pregnancy outcomes in women with uncontrolled asthma vs. mild asthma: a retrospective comparative analysis.Archives of gynecology and obstetrics · 2024Article
- Maternal asthma in Australian indigenous women and perinatal outcomes: A whole population-linked study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023Article
- Leukotrienes vs. Montelukast-Activity, Metabolism, and Toxicity Hints for Repurposing.Pharmaceuticals (Basel, Switzerland) · 2022Review
- A prospective study of preconception asthma and spontaneous abortion.Annals of epidemiology · 2022Article
- The safety of asthma medications during pregnancy and lactation: Clinical management and research priorities.The Journal of allergy and clinical immunology · 2021Article
- Early Sensory and Temperament Features in Infants Born to Mothers With Asthma: A Cross-Sectional Study.Frontiers in psychology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma is one of the most common chronic diseases, and prevalence, severity and medication may have an effect on pregnancy. We examined maternal asthma, asthma severity and control in relation to pregnancy complications, labour characteristics and perinatal outcomes.
methodsWe retrieved data on all singleton births from July 1, 2006 to December 31, 2009, and prescribed drugs and physician-diagnosed asthma on the same women from multiple Swedish registers. The associations were estimated with logistic regression.
resultsIn total, 266 045 women gave birth to 284 214 singletons during the study period. Maternal asthma was noted in 26 586 (9.4%) pregnancies. There was an association between maternal asthma and increased risks of pregnancy complications including preeclampsia or eclampsia (adjusted OR 1.15; 95% CI 1.06-1.24) and premature contractions (adj OR 1.52; 95% CI 1.29-1.80). There was also a significant association between maternal asthma and emergency caesarean section (adj OR 1.29; 95% CI 1.23-1.34), low birth weight, and small for gestational age (adj OR 1.23; 95% CI 1.13-1.33). The risk of adverse outcomes such as low birth weight increased with increasing asthma severity. For women with uncontrolled compared to those with controlled asthma the results for adverse outcomes were inconsistent displaying both increased and decreased OR for some outcomes.
conclusionMaternal asthma is associated with a number of serious pregnancy complications and adverse perinatal outcomes. Some complications are even more likely with increased asthma severity. With greater awareness and proper management, outcomes would most likely improve.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.