ReviewCentral European journal of urology2014
Secondary infertility and the aging male, overview.
Review in Central European journal of urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Exploring Single-Nucleotide Polymorphisms in Primary and Secondary Male Infertility.Medical sciences (Basel, Switzerland) · 2025Article
- Bidirectional Mendelian randomization to explore the causal relationships between the gut microbiota and male reproductive diseases.Scientific reports · 2024Article
- Secondary azoospermia after a successful natural pregnancy: a primary prospective study.Basic and clinical andrology · 2024Article
- Role of oxidative stress in male infertility.Reproduction & fertility · 2023Review
- Impact of Advanced Paternal Age on Fertility and Risks of Genetic Disorders in Offspring.Genes · 2023Review
- A case of hypogonadtropic hypogonadism due to hypophysitis discovered by secondary male infertility.IJU case reports · 2023Article
- Age-Related Decline of Male Fertility: Mitochondrial Dysfunction and the Antioxidant Interventions.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Sperm DNA fragmentation and male fertility: a retrospective study of 5114 men attending a reproductive center.Journal of assisted reproduction and genetics · 2021Article
- Association of Alcohol Intake and Semen Parameters in Men With Primary and Secondary Infertility: A Cross-Sectional Study.Frontiers in physiology · 2020Article
- High rate of detection of ultrasound signs of prostatitis in patients with HPV-DNA persistence on semen: role of ultrasound in HPV-related male accessory gland infection.Journal of endocrinological investigation · 2019Article
- Calretinin Participates in Regulating Steroidogenesis by PLC-CaScientific reports · 2018Article
- DNA methylation in spermatogenesis and male infertility.Experimental and therapeutic medicine · 2016Article
- Immune Infertility Should Be Positively Diagnosed Using an Accurate Method by Monitoring the Level of Anti-ACTL7a Antibody.Scientific reports · 2016Article
- Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring.Reproductive biology and endocrinology : RB&E · 2015Review
- Sexology of elderly man with secondary infertility.Central European journal of urology · 2014Article
- Metabolic syndrome in White-European men presenting for secondary couple's infertility: an investigation of the clinical and reproductive burden.Asian journal of andrologyArticle
- Effect of advanced paternal age on reproductive outcomes in IVF cycles of non-male-factor infertility: a retrospective cohort study.Asian journal of andrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOld men preparing themselves for marriage late in their lives might face infertility. Infertility in this group of men should be considered from a wider perspective, as they face any age-related health troubles that include, but are not limited to, androgen deficiency and psychological disorders that impede early conception. This review aims to shed light on the proper approach to this minority of secondarily infertile men. MATERIAL AND
methodsA comprehensive electronic English literature search was conducted, using various medical websites and books, for the factors that cause infertility in senior fathers. The physiology of geriatric males, together with their common comorbidities, were discussed.
resultsOld men presenting with secondary infertility should be approached differently. Aging, itself, has a significant impact on male sexual function, sperm parameters, and fertility; all of which contribute to poor fecundability, decreased fertilizing capacity, increased time to pregnancy, increased rate of DNA damage, high abortion rates and increased prevalence of fetal developmental failures. The complexity and the unknowns of the aging male physiology, together with the interaction of obstinate diseases the patient might have, make the issue very difficult to tackle.
conclusionsManagement should include the conventional way of treating young sufferers and further target the underlying causes, if known, along with the provision of geriatric, psychologic, and andrologic support.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.