SynthesisSocial cognitive and affective neuroscience2015
A meta-analysis of the anterior cingulate contribution to social pain.
Abstract readMeta-AnalysisReview
In one paragraph
Synthesis in Social cognitive and affective neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 9 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 9 pooled it
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
138 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Biological research on mental pain, social pain and other pains not primarily felt in the body: methodological systematic review.The British journal of psychiatry : the journal of mental science · 2025Pooled it
- Social pain: A systematic review on interventions.F1000Research · 2025Pooled it
- Does losing money truly hurt? The shared neural bases of monetary loss and pain.Human brain mapping · 2022Pooled it
- The neuroscience of social feelings: mechanisms of adaptive social functioning.Neuroscience and biobehavioral reviews · 2021Pooled it
- Social exclusion reliably engages the default network: A meta-analysis of Cyberball.NeuroImage · 2021Pooled it
- Social comparison in the brain: A coordinate-based meta-analysis of functional brain imaging studies on the downward and upward comparisons.Human brain mapping · 2018Pooled it
- Neural correlates of social exclusion across ages: A coordinate-based meta-analysis of functional MRI studies.NeuroImage · 2017Pooled it
- The neural and behavioral correlates of social evaluation in childhood.Developmental cognitive neuroscience · 2017Pooled it
- Pooled it
- Neurobiobehavioral responses to virtual social rejection in females-exploring the influence of oxytocin.Social cognitive and affective neuroscience · 2021Trial
- Machine Learning Identifies Large-Scale Reward-Related Activity Modulated by Dopaminergic Enhancement in Major Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Trial
- Brain connectivity dynamics during social interaction reflect social network structure.Proceedings of the National Academy of Sciences of the United States of America · 2017Trial
- Effects of serotonin 2A/1A receptor stimulation on social exclusion processing.Proceedings of the National Academy of Sciences of the United States of America · 2016Trial
- Neural Correlates of Prosocial Behavior: Compensating Social Exclusion in a Four-Player Cyberball Game.PloS one · 2016Trial
- Identifiable regional and neural network abnormalities in early childhood anxiety.JCPP advances · 2026Article
- Non-suicidal self-injury and digital ostracism: a novel smartphone-based paradigm capturing real-time responses to social media exclusion.Borderline personality disorder and emotion dysregulation · 2026Article
- Psilocybin effects on brain functional connectivity: a systematic review of fMRI studies.Discover mental health · 2026Review
- Mechanisms of entanglement: how a gendered world makes a gendered brain.Biology of sex differences · 2026Review
- Adolescent empathy predicts reduced neural responses to social rejection in adulthood.Development and psychopathology · 2026Article
- Heightened Susceptibility to Social Exclusion in Poor Sleepers: A Resting-State fMRI Study.Brain topography · 2026Article
78 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Jean-Yves RotgeINSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France INSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France jeanyves.rotge@mac.com.
Cedric LemogneINSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France INSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France INSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Pari
Sophie HinfrayINSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France INSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France.
Pascal HuguetINSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France INSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France.
Ouriel GrynszpanINSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France.
Eric TartourINSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France INSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France.
Nathalie GeorgeINSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France.
Philippe FossatiINSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France INSERM UMR 894, Centre Psychiatrie et Neurosciences, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, AP-HP, Hôpitaux Universitaires Paris Ouest, Service Universitaire de Psychiatrie de l'Adulte et du Sujet Agé, Paris, France, Aix-Marseille Université, Marseille, France, CNRS UMR 7290, Laboratoire de Psychologie Cognitive, Marseille, France, Université Pierre et Marie Curie, Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR 7222, Paris, France, Assistance Publique-Hôpitaux de Paris, Service d'Immunologie Biologique, Hôpital Européen Georges Pompidou, Paris, France, Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle, ICM, Social and Affective Neuroscience (SAN) Laboratory, F-75013 Paris, France, and AP-HP, Pitié-Salpêtrière Hospital, Department of Psychiatry, F-75013 Paris, France.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many functional magnetic resonance imaging studies have explored the neural correlates of social pain that results from social threat, exclusion, rejection, loss or negative evaluation. Although activations have consistently been reported within the anterior cingulate cortex (ACC), it remains unclear which ACC subdivision is particularly involved. To provide a quantitative estimation of the specific involvement of ACC subdivisions in social pain, we conducted a voxel-based meta-analysis. The literature search identified 46 articles that included 940 subjects, the majority of which used the cyberball task. Significant likelihoods of activation were found in both the ventral and dorsal ACC for both social pain elicitation and self-reported distress during social pain. Self-reported distress involved more specifically the subgenual and pregenual ACC than social pain-related contrasts. The cyberball task involved the anterior midcingulate cortex to a lesser extent than other experimental tasks. During social pain, children exhibited subgenual activations to a greater extent than adults. Finally, the ventro-dorsal gradient of ACC activations in cyberball studies was related to the length of exclusion phases. The present meta-analysis contributes to a better understanding of the role of ACC subdivisions in social pain, and it could be of particular importance for guiding future studies of social pain and its neural underpinnings.
Indexed as
Social EnvironmentAdultCerebral CortexChildGyrus CinguliHumansMagnetic Resonance ImagingPainanterior cingulate cortexcyberballfunctional magnetic resonance imagingmeta-analysissocial pain
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