Evidence map›Paper›PMID 25139878›Full record

ArticleStroke2014

Social network, social support, and risk of incident stroke: Atherosclerosis Risk in Communities study.

Mako Nagayoshi, Susan A Everson-Rose, Hiroyasu Iso, Thomas H Mosley, Kathryn M Rose, Pamela L Lutsey

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 4 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 86 citations in OpenAlex.

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  19. Racial-Ethnic disparities in stroke prevalence among patients with heart failure.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mako NagayoshiFrom the Division of Epidemiology and Community Health (M.N., P.L.L.) and Department of Medicine (S.A.E.-R.), University of Minnesota, Minneapolis; Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan (M.N.); Department of Medicine, Osaka University, Suita, Japan (H.I.); Departments of Geriatrics/Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS (T.H.M.); and Department of Epidemiology, University of North Carolina at Chapel Hill (K.M.R.). mnagayoshi@nagasaki-u.ac.jp.
Susan A Everson-RoseFrom the Division of Epidemiology and Community Health (M.N., P.L.L.) and Department of Medicine (S.A.E.-R.), University of Minnesota, Minneapolis; Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan (M.N.); Department of Medicine, Osaka University, Suita, Japan (H.I.); Departments of Geriatrics/Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS (T.H.M.); and Department of Epidemiology, University of North Carolina at Chapel Hill (K.M.R.).
Hiroyasu IsoFrom the Division of Epidemiology and Community Health (M.N., P.L.L.) and Department of Medicine (S.A.E.-R.), University of Minnesota, Minneapolis; Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan (M.N.); Department of Medicine, Osaka University, Suita, Japan (H.I.); Departments of Geriatrics/Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS (T.H.M.); and Department of Epidemiology, University of North Carolina at Chapel Hill (K.M.R.).
Thomas H MosleyFrom the Division of Epidemiology and Community Health (M.N., P.L.L.) and Department of Medicine (S.A.E.-R.), University of Minnesota, Minneapolis; Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan (M.N.); Department of Medicine, Osaka University, Suita, Japan (H.I.); Departments of Geriatrics/Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS (T.H.M.); and Department of Epidemiology, University of North Carolina at Chapel Hill (K.M.R.).
Kathryn M RoseFrom the Division of Epidemiology and Community Health (M.N., P.L.L.) and Department of Medicine (S.A.E.-R.), University of Minnesota, Minneapolis; Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan (M.N.); Department of Medicine, Osaka University, Suita, Japan (H.I.); Departments of Geriatrics/Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS (T.H.M.); and Department of Epidemiology, University of North Carolina at Chapel Hill (K.M.R.).
Pamela L LutseyFrom the Division of Epidemiology and Community Health (M.N., P.L.L.) and Department of Medicine (S.A.E.-R.), University of Minnesota, Minneapolis; Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan (M.N.); Department of Medicine, Osaka University, Suita, Japan (H.I.); Departments of Geriatrics/Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS (T.H.M.); and Department of Epidemiology, University of North Carolina at Chapel Hill (K.M.R.).
Osaka University · JPUniversity of Mississippi Medical Center · USNagasaki University · JP

Funding

FIELD CENTER FOR CCSPN01HC055019 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI FOLSOM, AARON R · 1985 to 2000
$748k
RAPID IMMUNODETECTION OF CARDIAC PROTEINS IN WHOLE BLOODR41HL055019 · NHLBI · SELECTIVE TECHNOLOGIES, INC. · PI MARTIN, GLENN B · 1995 to 1995
–
NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS N01 HC055019
6 · The paper itself

Abstract

background and purposeHaving a small social network and lack of social support have been associated with incident coronary heart disease; however, epidemiological evidence for incident stroke is limited. We assessed the longitudinal association of a small social network and lack of social support with risk of incident stroke and evaluated whether the association was partly mediated by vital exhaustion and inflammation.

methodsThe Atherosclerosis Risk in Communities study measured social network and social support in 13 686 men and women (mean, 57 years; 56% women; 24% black; 76% white) without a history of stroke. Social network was assessed by the 10-item Lubben Social Network Scale and social support by a 16-item Interpersonal Support Evaluation List-Short Form.

resultsDuring a median follow-up of 18.6 years, 905 incident strokes occurred. Relative to participants with a large social network, those with a small social network had a higher risk of stroke (hazard ratio [95% confidence interval], 1.44 [1.02-2.04]) after adjustment for demographics, socioeconomic variables, marital status, behavioral risk factors, and major stroke risk factors. Vital exhaustion, but not inflammation, partly mediated the association between a small social network and incident stroke. Social support was unrelated to incident stroke.

conclusionsIn this sample of US community-dwelling men and women, having a small social network was associated with excess risk of incident stroke. As with other cardiovascular conditions, having a small social network may be associated with a modestly increased risk of incident stroke.

Indexed as

Social SupportAgedAtherosclerosisFemaleHumansIncidenceMaleMiddle AgedRisk FactorsStrokeepidemiologyinflammationsocial supportstroke

Identifiers

PMID25139878
PMCPMC4201236
OpenAlexW2141438527

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.