Evidence map›Paper›PMID 25139125›Full record

ArticleJournal of psychosomatic research2014

Depression and risk of hospitalization for pneumonia in a cohort study of older Americans.

Dimitry S Davydow, Catherine L Hough, Kara Zivin, Kenneth M Langa, Wayne J Katon

Abstract read
In one paragraph

Article in Journal of psychosomatic research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dimitry S DavydowDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA. Electronic address: ddavydo1@u.washington.edu.
Catherine L HoughDepartment Internal Medicine, University of Washington, Seattle, WA, USA.
Kara ZivinAnn Arbor Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI, USA; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA; Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Kenneth M LangaAnn Arbor Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI, USA; Institute for Social Research, University of Michigan, Ann Arbor, MI, USA; Department of Medicine, University of Michigan, Ann Arbor, MI, USA.
Wayne J KatonDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Institute of Translational Health SciencesKL2TR000421 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$12.6M
The Cost of DementiaR01AG030155 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 2007 to 2011
$3.1M
The structure and outcomes of critical care transfer networkK08HL091249 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI IWASHYNA, THEODORE J · 2008 to 2012
$661k
NCATS NIH HHS KL2 TR000421NHLBI NIH HHS K08 HL091249NIA NIH HHS R01 AG030155NIA NIH HHS U01 AG009740NIA NIH HHS U01 AG09740
6 · The paper itself

Abstract

objectiveThe aim of this study is to determine if depression is independently associated with risk of hospitalization for pneumonia after adjusting for demographics, medical comorbidity, health-risk behaviors, baseline cognition and functional impairments.

methodsThis secondary analysis of prospectively collected data examined a population-based sample of 6704 Health and Retirement Study (HRS) (1998-2008) participants>50years old who consented to have their interviews linked to their Medicare claims and were without a dementia diagnosis. The eight-item Center for Epidemiologic Studies Depression Scale and/or International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) depression diagnoses were used to identify baseline depression. ICD-9-CM diagnoses were used to identify hospitalizations for which the principal discharge diagnosis was for bacterial or viral pneumonia. The odds of hospitalization for pneumonia for participants with depression relative to those without depression were estimated using logistic regression models. Population attributable fractions were calculated to determine the extent that hospitalizations for pneumonia could be attributable to depression.

resultsAfter adjusting for demographic characteristics, clinical factors, and health-risk behaviors, depression was independently associated with increased odds of hospitalization for pneumonia (odds ratio [OR]: 1.28, 95% confidence interval [95%CI]: 1.08, 1.53). This association persisted after adjusting for baseline cognition and functional impairments (OR: 1.24, 95%CI: 1.03, 1.50). In this cohort, 6% (95%CI: 2%, 10%) of hospitalizations for pneumonia were potentially attributable to depression.

conclusionDepression is independently associated with increased odds of hospitalization for pneumonia. This study provides additional rationale for integrating mental health care into medical settings in order to improve outcomes for older adults.

Indexed as

PneumoniaAgedAged, 80 and overCohort StudiesComorbidityDepressionDepressive DisorderFemaleHospitalizationHumansLogistic ModelsMaleMiddle AgedOdds RatioRisk AssessmentRisk FactorsDepressionHospitalizationOutcome assessment (health care)Pneumonia

Identifiers

PMID25139125
PMCPMC4259844

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.