ArticleClinical cardiology2014
Rationale and design of the Henry Ford Exercise Testing Project (the FIT project).
Article in Clinical cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- The effects of hot-water immersion on cardiovascular and cardiorespiratory health of healthy adults: A systematic review and meta-analysis.Physiological reports · 2026Pooled it
- Equipment-free, unsupervised high intensity interval training elicits significant improvements in the physiological resilience of older adults.BMC geriatrics · 2022Trial
- Coronary Artery Calcium for Risk Stratification of Heart Failure Mortality: The Coronary Artery Calcium Consortium.Journal of cardiac failure · 2025Article
- FIT calculator: a multi-risk prediction framework for medical outcomes using cardiorespiratory fitness data.Scientific reports · 2024Article
- The Role of Electrocardiographic Exercise Testing for the Possibility of Permanent Pacemaker Implantation in Patients with Sinus Bradycardia.Vascular health and risk management · 2024Article
- Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio-Vascular-Skeletal Muscle Coupling.Journal of clinical medicine · 2023Article
- Exercise and Experiments of Nature.Comprehensive Physiology · 2023Article
- Coronary Artery Calcium Dispersion and Cause-Specific Mortality.The American journal of cardiology · 2023Article
- Discordance Between Coronary Artery Calcium Area and Density Predicts Long-Term Atherosclerotic Cardiovascular Disease Risk.JACC. Cardiovascular imaging · 2022Article
- Estimating Cardiorespiratory Fitness Without Exercise Testing or Physical Activity Status in Healthy Adults: Regression Model Development and Validation.JMIR public health and surveillance · 2022Article
- Mean Versus Peak Coronary Calcium Density on Non-Contrast CT: Calcium Scoring and ASCVD Risk Prediction.JACC. Cardiovascular imaging · 2022Article
- Comparing Risk Scores in the Prediction of Coronary and Cardiovascular Deaths: Coronary Artery Calcium Consortium.JACC. Cardiovascular imaging · 2021Article
- Prediction of High-Altitude Cardiorespiratory Fitness Impairment Using a Combination of Physiological Parameters During Exercise at Sea Level and Genetic Information in an Integrated Risk Model.Frontiers in cardiovascular medicine · 2021Article
- Exercise capacity is associated with hospital readmission among patients with diabetes.BMJ open diabetes research & care · 2020Article
- Coronary Artery Calcium and the Age-Specific Competing Risk of Cardiovascular Versus Cancer Mortality: The Coronary Artery Calcium Consortium.The American journal of medicine · 2020Article
- Association of Body Mass Index With Coronary Artery Calcium and Subsequent Cardiovascular Mortality: The Coronary Artery Calcium Consortium.Circulation. Cardiovascular imaging · 2020Article
- Coronary Artery Calcium as a Synergistic Tool for the Age- and Sex-Specific Risk of Cardiovascular and Cancer Mortality: The Coronary Artery Calcium Consortium.Journal of the American Heart Association · 2020Article
- Long-Term All-Cause and Cause-Specific Mortality in Asymptomatic Patients With CAC ≥1,000: Results From the CAC Consortium.JACC. Cardiovascular imaging · 2020Article
- On the interpretability of machine learning-based model for predicting hypertension.BMC medical informatics and decision making · 2019Article
- Association of Coronary Artery Calcium With Long-term, Cause-Specific Mortality Among Young Adults.JAMA network open · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although physical fitness is a powerful prognostic marker in clinical medicine, most cardiovascular population-based studies do not have a direct measurement of cardiorespiratory fitness. In line with the call from the National Heart Lung and Blood Institute for innovative, low-cost, epidemiologic studies leveraging electronic medical record (EMR) data, we describe the rationale and design of the Henry Ford ExercIse Testing Project (The FIT Project). The FIT Project is unique in its combined use of directly measured clinical exercise data retrospective collection of medical history and medication treatment data at the time of the stress test, retrospective supplementation of supporting clinical data using the EMR and administrative databases and epidemiologic follow-up for cardiovascular events and total mortality via linkage with claims files and the death registry. The FIT Project population consists of 69 885 consecutive physician-referred patients (mean age, 54 ± 10 years; 54% males) who underwent Bruce protocol treadmill stress testing at Henry Ford Affiliated Hospitals between 1991 and 2009. Patients were followed for the primary outcomes of death, myocardial infarction, and need for coronary revascularization. The median estimated peak metabolic equivalent (MET) level was 10, with 17% of the patients having a severely reduced fitness level (METs < 6). At the end of the follow-up duration, 15.9%, 5.6%, and 6.7% of the patients suffered all-cause mortality, myocardial infarction, or revascularization procedures, respectively. The FIT Project is the largest study of physical fitness to date. With its use of modern electronic clinical epidemiologic techniques, it is poised to answer many clinically relevant questions related to exercise capacity and prognosis.
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