Evidence map›Paper›PMID 25138549›Full record

ArticleWiener klinische Wochenschrift2014

Dabigatran: patient management in specific clinical settings.

Paul Alexander Kyrle, Konrad Binder, Sabine Eichinger, Reinhold Függer, Bernd Gollackner, J Michael Hiesmayr, Kurt Huber, Wielfried Lang, Peter Perger, Peter Quehenberger and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Wiener klinische Wochenschrift, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Paul Alexander KyrleDepartment of Medicine I, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria, paul.kyrle@meduniwien.ac.at.
Konrad Binder
Sabine Eichinger
Reinhold Függer
Bernd Gollackner
J Michael Hiesmayr
Kurt Huber
Wielfried Lang
Peter Perger
Peter Quehenberger
Franz X Roithinger
Sabine Schmaldienst
Ansgar Weltermann
Hans Domanovits
Medical University of Vienna · ATKrankenhaus der Elisabethinen · ATKlinik Hietzing · ATLandesklinikum Korneuburg · ATUniversitätsklinikum St. Pölten · ATWilhelminen Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dabigatran, a direct thrombin inhibitor, is licensed for the prevention of venous thromboembolism after knee and hip replacement, the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation and for the treatment of acute venous thromboembolism. As dabigatran has a favourable benefit-risk profile, it is being increasingly used. Dabigatran differs from vitamin K antagonists as regards its pharmacological characteristics and its impact on certain laboratory tests, and also in the lack of a direct antagonist that can reverse dabigatran-induced anticoagulation. In emergency settings such as acute bleeding, emergency surgery, acute coronary syndrome, thrombolysis for ischaemic stroke or overdosing, specific strategies are required. A working group of experts from various disciplines has developed strategies for the management of dabigatran-treated patients in emergency settings.

Indexed as

Practice Guidelines as TopicAntithrombinsArthroplasty, ReplacementAustriaBenzimidazolesbeta-AlanineDabigatranHemorrhageHumansVenous ThromboembolismAntithrombinsBenzimidazolesbeta-AlanineDabigatran

Identifiers

PMID25138549
PMCPMC4165862
OpenAlexW92746139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.