Evidence map›Paper›PMID 2513807›Full record

ArticleThe Biochemical journal1989

Adipocyte plasma-membrane Gi and Gs in insulinopenic diabetic patients.

J J Ohisalo, H L Vikman, S Ranta, M D Houslay, G Milligan

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J J OhisaloDepartment of Medical Chemistry, University of Helsinki, Finland.
H L Vikman
S Ranta
M D Houslay
G Milligan
University of Helsinki · FIHelsinki University Hospital · FI

Funding

Wellcome Trust
6 · The paper itself

Abstract

Changes in the amounts and functions of G-proteins have been reported in diabetic rats. We determined the Gi/Gs ratio of adipocyte plasma membranes in six insulinopenic diabetic patients and matched controls by immunoblotting with antisera against synthetic peptides corresponding to regions of G-proteins. No consistent changes in the Gi/Gs ratio were observed. It is still possible that the functional status of the G-proteins may be altered in diabetes.

Indexed as

Adipose TissueBlotting, WesternCell MembraneDiabetes MellitusGTP-Binding ProteinsHumansInsulinGTP-Binding ProteinsInsulin

Identifiers

PMID2513807
PMCPMC1133575
OpenAlexW2419167846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.