Evidence map›Paper›PMID 25137591›Full record

ArticleCurrent biology : CB2014

Evolution: ctenophore genomes and the origin of neurons.

Heather Marlow, Detlev Arendt

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Beyond synapses: cytoplasmic connections in brain function and evolution.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  2. Review
  3. Article
  4. Evolutionary transitions in learning and cognition.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  5. Neural versus alternative integrative systems: molecular insights into origins of neurotransmitters.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. ADAR RNA editing below the backbone.RNA (New York, N.Y.) · 2017
    Review
  11. Small molecule modulation of voltage gated sodium channels.Current opinion in structural biology · 2017
    Review
  12. Article
  13. Loss of neurogenesis in Hydra leads to compensatory regulation of neurogenic and neurotransmission genes in epithelial cells.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016
    Article
  14. Independent origins of neurons and synapses: insights from ctenophores.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016
    Review
  15. Review
  16. Article
  17. The ancestral gene repertoire of animal stem cells.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  18. Early metazoan life: divergence, environment and ecology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
  19. Gastric pouches and the mucociliary sole: setting the stage for nervous system evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
  20. An option space for early neural evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Heather MarlowDevelopmental Biology Unit, European Molecular Biology Laboratory, Meyerhofstraße 1, 69012 Heidelberg, Germany. Electronic address: marlow@embl.de.
Detlev ArendtDevelopmental Biology Unit, European Molecular Biology Laboratory, Meyerhofstraße 1, 69012 Heidelberg, Germany. Electronic address: arendt@embl.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent sequencing of ctenophore genomes opens a new era in the study of this unique and phylogenetically distant group. The presence of neurodevelopmental genes, pre- and postsynaptic modules, and transmitter molecules is consistent with a single origin of neurons.

Indexed as

Biological EvolutionEvolution, MolecularNervous SystemAnimalsCell LineageCtenophoraGenome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.