Evidence map›Paper›PMID 25136635›Full record

ArticleBioMed research international2014

Pathological feature and immunoprofile of cystitis glandularis accompanied with upper urinary tract obstruction.

Aihua Li, Jun Zhou, Honghai Lu, Xiaoming Zuo, Sikuan Liu, Feng Zhang, Weiwu Li, Wei Fang, Binghui Zhang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The role of steroid treatment in intractable cystitis glandularis: A case report and literature review.Canadian Urological Association journal = Journal de l'Association des urologues du Canada
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Aihua LiDepartment of Urology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China.
Jun ZhouDepartment of Urology, Huadong Hospital Affiliated with Fudan University, Shanghai 200040, China.
Honghai LuDepartment of Urology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China.
Xiaoming ZuoDepartment of Urology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China.
Sikuan LiuDepartment of Urology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China.
Feng ZhangDepartment of Urology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China.
Weiwu LiDepartment of Urology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China.
Wei FangDepartment of Urology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China.
Binghui ZhangDepartment of Urology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China.
Yangpu Hospital of Tongji University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the pathological feature and immunoprofile of immunoprofile accompanied with upper urinary tract obstruction and the immunoprofile in various types of glandular cystitis.

methodsPathological sections from 31 cases of cystitis glandularis with upper urinary tract obstruction and 34 cases of cystitis glandularis without upper urinary tract obstruction were observed as pathological feature on microscopy. Meanwhile, an immunohistochemical analysis was employed to determine the expression of p53, Ki67, p21, MMP-9, MUC1, MUC2, and COX-2.

resultsIn the two groups, main pathological type was transitional epithelial, followed by intestinal epithelial; other types were a few, and the difference between the two groups was not significant. All immunohistochemical expressions of p53, Ki67, p21, MMP-9, MUC1, MUC2, and COX-2 were positive in varying degrees, and there was no significant difference between the groups. Transitional epithelial type was compared with mixed type; the difference of COX-2 was significant, P < 0.05. The differences of immunohistochemical expression among other different pathologic types were not significant.

conclusionsIt is suggested that glandular cystitis accompanied with upper urinary tract obstruction shares the same pathological feature and immunoprofile as that without upper urinary tract obstruction. No significant differences of immunohistochemical expression in tissue are in cystitis glandularis with different pathological types.

Indexed as

AdultAgedAged, 80 and overCystitisEpithelial CellsFemaleGene Expression RegulationHumansIntestinal MucosaIntestinesMaleMiddle AgedPrecancerous ConditionsUrinary BladderUrinary Tract

Identifiers

PMID25136635
PMCPMC4127228
OpenAlexW2061354102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.