Evidence map›Paper›PMID 25136603›Full record

ReviewBioMed research international2014

Anterior segment optical coherence tomography imaging of conjunctival filtering blebs after glaucoma surgery.

Rodolfo Mastropasqua, Vincenzo Fasanella, Luca Agnifili, Claudia Curcio, Marco Ciancaglini, Leonardo Mastropasqua

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05790408 (Anterior-segment OCT), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05790408 naterminatednot on this mapstarted 2020, after this paper: background citation

Anterior-segment OCT (AS-OCT) and Intraoperative OCT (iOCT) for Trans- Conjunctival Needle Revision (TCNR) of Trabeculectomy Bleb

TypeinterventionalSponsorNorthwestern UniversityRan2020 to 2022Enrolled10ConditionsGlaucoma, Glaucoma Following SurgeryArmsDigital microscope integrated with intraoperative OCT (Zeiss Artevo 800, Carl Zeiss Meditec AG), Spectralis Anterior-segment OCT (AS-OCT) (Heidelberg Engineering)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Two-years efficacy and safety of bleb forming devices in uncontrolled glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. Article
  5. Review
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  9. Does mitomycin-C concentration have any influence on XEN45 gel stent outcomes in a real-world setting?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Assessing the Status of Filtering Blebs at 5 Year Post- Trabeculectomy.Open access Macedonian journal of medical sciences · 2019
    Article
  15. Comparison of conjunctival vascularity changes using optical coherence tomography angiography after trabeculectomy and phacotrabeculectomy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rodolfo MastropasquaOphthalmology Unit, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, 53593 Verona, Italy.
Vincenzo FasanellaOphthalmic Clinic, Department of Medicine and Aging Science, Ophthalmic Clinic, University G. d'Annunzio of Chieti-Pescara, Via dei Frentani 114, 66100 Chieti, Italy.
Luca AgnifiliOphthalmic Clinic, Department of Medicine and Aging Science, Ophthalmic Clinic, University G. d'Annunzio of Chieti-Pescara, Via dei Frentani 114, 66100 Chieti, Italy.ORCID 0000-0002-1625-6305
Claudia CurcioExcellence Eye Research Center, CeSI, G. d'Annunzio University of Chieti-Pescara, 66100 Chieti, Italy.
Marco CiancagliniOphthalmic Clinic, Department of Surgical Science, University of L'Aquila, 67100 L'Aquila, Italy.
Leonardo MastropasquaOphthalmic Clinic, Department of Medicine and Aging Science, Ophthalmic Clinic, University G. d'Annunzio of Chieti-Pescara, Via dei Frentani 114, 66100 Chieti, Italy.ORCID 0000-0003-4890-3834
University of Chieti-Pescara · ITUniversity of L'Aquila · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Time domain (TD) and spectral domain (SD) optical coherence tomography (OCT) are cross-sectional, noncontact, high-resolution diagnostic modalities for posterior and anterior segment (AS) imaging. The AS-OCT provides tomographic imaging of the cornea, iris, lens, and anterior chamber (AC) angle in several ophthalmic diseases. In glaucoma, AS-OCT is utilized to evaluate the morphology of AS structures involved in the pathogenesis of the disease, to obtain morphometric measures of the AC, to evaluate the suitability for laser or surgical approaches, and to assess modifications after treatment. In patients undergoing surgery, AS-OCT is crucial in the evaluation of the filtering bleb functionality, permitting a combined qualitative and quantitative analysis. In this field, AS-OCT may help clinicians in distinguishing between functioning and nonfunctioning blebs by classifying their macroscopic morphology, describing bleb-wall features, bleb cavity, and scleral opening. This information is critical in recognizing signs of filtration failure earlier than the clinical approach and in planning the appropriate timing for management procedures in failing blebs. In this review, we summarize the applications of AS-OCT in the conjunctival bleb assessment.

Indexed as

Diagnostic ImagingAnterior Eye SegmentGlaucoma, Open-AngleHumansIntraocular PressureOphthalmologic Surgical ProceduresRadiographyScleraTomography, Optical Coherence

Identifiers

PMID25136603
PMCPMC4127298
OpenAlexW1972517249

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.